Herbal medicine AnoSpray suppresses proinflammatory cytokines COX-2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds.
AnoSpray
COX-2
RANTES
anorectal disorders
cytokine
cytotoxicity
inflammation
pilospray
Journal
Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
01
06
2021
accepted:
30
09
2021
entrez:
23
12
2021
pubmed:
24
12
2021
medline:
24
12
2021
Statut:
ppublish
Résumé
Hemorrhoids, anal fistula and fissure are common anorectal complications. Anorectal diseases are associated with severe pain, inflammation, swelling, itching and bleeding. These diseases may be managed with different medical treatments or surgical procedures, depending on their severity. Surgical procedures, however, are highly invasive and are associated with higher costs and the possibility of recurrence. In addition, surgical removal of fistula-in-ano leads to the formation of perineal wounds. Therefore, developing therapeutic interventions that are effective in alleviating inflammation and pain are desirable for the effective management of anorectal diseases. Herbal compounds have previously been indicated to suppress inflammation and pain in different pathological conditions. The aim of the present study was to examine the effects elicited by a polyherbal formulation, AnoSpray
Identifiants
pubmed: 34938368
doi: 10.3892/etm.2021.11009
pii: ETM-23-1-11009
pmc: PMC8688930
doi:
Types de publication
Journal Article
Langues
eng
Pagination
86Informations de copyright
Copyright: © Porwal et al.
Déclaration de conflit d'intérêts
GB and RB are employees of Healing Hands & Herbs Pvt. Ltd., who provided the pharamceutical product used in this study.
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