Co-occurring medical and behavioural conditions in children with Down syndrome with or without ADHD symptom presentation.

Attention Deficit Disorder with Hyperactivity / complications Attention Deficit and Disruptive Behavior Disorders Child Down Syndrome / epidemiology Humans Parents Problem Behavior
ADHD Behaviour Co-occurring medical conditions Down syndrome Symptoms Trisomy 21

Journal

Journal of intellectual disability research : JIDR
ISSN: 1365-2788
Titre abrégé: J Intellect Disabil Res
Pays: England
ID NLM: 9206090

Informations de publication

Date de publication:
03 2022
Historique:
revised: 01 12 2021
received: 12 08 2021
accepted: 02 12 2021
pubmed: 24 12 2021
medline: 11 5 2022
entrez: 23 12 2021
Statut: ppublish

Résumé

Co-occurring attention deficit hyperactivity disorder (ADHD) is a challenge to characterise in the presence of other medical conditions commonly present in children with Down syndrome (DS). The current study examined differences among children with DS with or without ADHD symptomatology in terms of demographics, developmental level, co-occurring medical conditions, and parent and teacher ratings of behaviour and executive functioning. Parents and teachers of 108 school-age children with DS provided ratings of ADHD symptoms, behaviour problems and executive functioning skills. Children with DS and ADHD symptom presentation, as identified by a scoring algorithm, were compared with those without ADHD symptom presentation on demographic characteristics, developmental level, co-occurring medical conditions and parent-report and teacher-report measures of behaviours and executive functioning. Sleep disorders, disruptive behaviour disorder, allergies and seizures were more common in children with DS and ADHD symptom presentation than in children without ADHD symptom presentation. After controlling for ADHD medication use, children with DS and ADHD symptom presentation had poorer performance than those without ADHD symptom presentation on parent behaviour ratings, teacher behaviour ratings and parent but not teacher ratings of executive functioning. No significant group differences in demographic characteristics or developmental level were identified. Higher rates of co-occurring medical conditions present in children with DS and ADHD symptom presentation support the need for thorough differential diagnoses. The different pattern of group differences between parent-report and teacher-report has implications for diagnostic practices across settings as well as for treatment.

Sections du résumé

BACKGROUND
Co-occurring attention deficit hyperactivity disorder (ADHD) is a challenge to characterise in the presence of other medical conditions commonly present in children with Down syndrome (DS). The current study examined differences among children with DS with or without ADHD symptomatology in terms of demographics, developmental level, co-occurring medical conditions, and parent and teacher ratings of behaviour and executive functioning.
METHODS
Parents and teachers of 108 school-age children with DS provided ratings of ADHD symptoms, behaviour problems and executive functioning skills. Children with DS and ADHD symptom presentation, as identified by a scoring algorithm, were compared with those without ADHD symptom presentation on demographic characteristics, developmental level, co-occurring medical conditions and parent-report and teacher-report measures of behaviours and executive functioning.
RESULTS
Sleep disorders, disruptive behaviour disorder, allergies and seizures were more common in children with DS and ADHD symptom presentation than in children without ADHD symptom presentation. After controlling for ADHD medication use, children with DS and ADHD symptom presentation had poorer performance than those without ADHD symptom presentation on parent behaviour ratings, teacher behaviour ratings and parent but not teacher ratings of executive functioning. No significant group differences in demographic characteristics or developmental level were identified.
CONCLUSIONS
Higher rates of co-occurring medical conditions present in children with DS and ADHD symptom presentation support the need for thorough differential diagnoses. The different pattern of group differences between parent-report and teacher-report has implications for diagnostic practices across settings as well as for treatment.

Identifiants

DOI: 10.1111/jir.12911 PMID: 34939724 PMC: PMC8816818
pubmed: 34939724
doi: 10.1111/jir.12911
pmc: PMC8816818
mid: NIHMS1761511
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

282-296

Subventions

Organisme : NICHD NIH HHS
ID : R61 HD100934
Pays : United States
Organisme : NICHD NIH HHS
ID : R21 HD082307
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD093754
Pays : United States

Informations de copyright

© 2021 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

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Auteurs

A J Esbensen (AJ)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
ORCID: 0000-0003-2649-7791

L B Vincent (LB)

School of Human Services, University of Cincinnati, Cincinnati, OH, USA.

J N Epstein (JN)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

K Kamimura-Nishimura (K)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

S Wiley (S)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

K Angkustsiri (K)

MIND Institute, University of California, Davis, Davis, CA, USA.
Department of Pediatrics, University of California, Davis, Davis, CA, USA.

L Abbeduto (L)

MIND Institute, University of California, Davis, Davis, CA, USA.
Department of Psychiatry and Behavioral Sciences, University of California, Davis, Davis, CA, USA.

D Fidler (D)

Department of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.

J S Anixt (JS)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

T E Froehlich (TE)

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles du développement neurologique › Troubles déficitaires de l'attention et du comportement perturbateur › Trouble déficitaire de l'attention avec hyperactivité › Co-occurring medical and behavioural...
questionsmedicales.fr › Troubles mentaux › Troubles du développement neurologique › Troubles déficitaires de l'attention et du comportement perturbateur › Co-occurring medical and behavioural...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Co-occurring medical and behavioural...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Maladies chromosomiques › Syndrome de Down › Co-occurring medical and behavioural...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Co-occurring medical and behavioural...
questionsmedicales.fr › Personnes › Parents › Co-occurring medical and behavioural...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement de l'enfant › Comportement déviant › Co-occurring medical and behavioural...