The QOSMOS Study: Pharmacist-Led Multicentered Observational Study on Quality of Life in Multiple Sclerosis.

MS-QoL54 disease-modifying drugs hospital pharmacist multiple sclerosis quality of life

Journal

Neurology international
ISSN: 2035-8385
Titre abrégé: Neurol Int
Pays: Switzerland
ID NLM: 101551564

Informations de publication

Date de publication:
03 Dec 2021
Historique:
received: 07 10 2021
revised: 20 11 2021
accepted: 24 11 2021
entrez: 23 12 2021
pubmed: 24 12 2021
medline: 24 12 2021
Statut: epublish

Résumé

Health-related quality of life is frequently included in patient-reported outcomes aimed at evaluating the effectiveness of disease-modifying drugs for multiple sclerosis, but recent data about Italian patients are missing. A multicenter observational and cross-sectional study was performed by students of hospital pharmacy to update existing data on quality of life and to correlate it with the pharmacological and medical history of patients. Quality of life (QoL) was assessed using the MS-QoL54 questionnaire, and the pharmacist collected patients' characteristics, medical and pharmacological history, and Expanded Disability Status Scale (EDSS). Three hundred and forty-nine patients with multiple sclerosis were recruited from 16 centers between May 2018 and June 2019 (median age = 44.1 years; 68.9% women). The composite indexes of physical and mental well-being showed direct correlation with each other (R = 0.826;

Identifiants

pubmed: 34940751
pii: neurolint13040065
doi: 10.3390/neurolint13040065
pmc: PMC8706851
doi:

Types de publication

Journal Article

Langues

eng

Pagination

682-694

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Auteurs

Vera Damuzzo (V)

Department of Pharmaceutical and Pharmacological Sciences, School of Hospital Pharmacy, University of Padua, 35122 Padua, Italy.
National Association of Hospital Pharmacy Students-ReNaSFO, 20122 Milan, Italy.

Laura Agnoletto (L)

Pharmacy, Santa Maria della Misericordia Hospital, 45100 Rovigo, Italy.

Roberta Rampazzo (R)

Regional Pharmaceutical Office, Veneto Region, 30125 Venice, Italy.

Francesca Cammalleri (F)

Department of Pharmaceutical Sciences, School of Hospital Pharmacy, University of Milan, 20122 Milan, Italy.

Luca Cancanelli (L)

Department of Pharmaceutical Sciences, School of Hospital Pharmacy, University of Milan, 20122 Milan, Italy.

Marco Chiumente (M)

Italian Society of Clinical Pharmacy and Therapeutics-SIFaCT, 20159 Milan, Italy.

Stefano Costantino (S)

Department of Drug Science and Technology, School of Hospital Pharmacy, University of Turin, 10124 Turin, Italy.

Silvia Michielan (S)

Department of Pharmaceutical and Pharmacological Sciences, School of Hospital Pharmacy, University of Padua, 35122 Padua, Italy.

Federica Milani (F)

Department of Pharmaceutical and Pharmacological Sciences, School of Hospital Pharmacy, University of Padua, 35122 Padua, Italy.

Alessia Sartori (A)

Department of Food and Drug, School of Hospital Pharmacy, University of Parma, 43121 Parma, Italy.

Melania Rivano (M)

Department of Pharmaceutical Sciences, School of Hospital Pharmacy, University of Milan, 20122 Milan, Italy.

Daniele Mengato (D)

Italian Society of Clinical Pharmacy and Therapeutics-SIFaCT, 20159 Milan, Italy.
Hospital Pharmacy Department, Azienda Ospedale-Università of Padova, 35121 Padua, Italy.

Classifications MeSH