Sex-Specific Association of Serum Anti-Oxidative Capacity and Leukocyte Telomere Length.
leucocyte telomere length
lifestyle changes
oxidative stress
telomerase
telomere shortening
total antioxidative capacity
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
28 Nov 2021
28 Nov 2021
Historique:
received:
02
11
2021
revised:
25
11
2021
accepted:
26
11
2021
entrez:
24
12
2021
pubmed:
25
12
2021
medline:
25
12
2021
Statut:
epublish
Résumé
Telomeres are a crucial factor in the preservation of genomic integrity, and an elevated risk for diseases such as cancer and cardiovascular events is related to shortened telomeres. However, telomere deterioration could be caused by factors such as chronic oxidative stress and inflammation, which are promoted by an imbalance among reactive oxygen species (ROS) and antioxidants. In this cross-sectional study, we investigated the relationship between telomeres and oxidative stress. The serum leucocyte telomer length (LTL), serum total antioxidant capacity (TAC) and the total serum lipid panel of 180 healthy athletic volunteers (90 males, 90 females) were measured Additionally, a questionnaire about sports behaviour and the type of training was completed. We observed a positive significant relation between serum LTL and TAC in the male group (cc = 3.4/
Identifiants
pubmed: 34943011
pii: antiox10121908
doi: 10.3390/antiox10121908
pmc: PMC8750675
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Public Health Nutr. 2006 Dec;9(8A):1136-40
pubmed: 17378953
Exp Gerontol. 2010 Mar;45(3):171-2
pubmed: 20005282
Drugs. 2002;62(17):2421-31
pubmed: 12421100
Nucleic Acids Res. 2002 May 15;30(10):e47
pubmed: 12000852
Antioxidants (Basel). 2021 Jun 28;10(7):
pubmed: 34203235
Annu Rev Biochem. 1984;53:163-94
pubmed: 6383193
Circ Res. 2004 Apr 2;94(6):768-75
pubmed: 14963003
Nat Rev Genet. 2005 Aug;6(8):611-22
pubmed: 16136653
Biomolecules. 2021 Aug 25;11(9):
pubmed: 34572477
Mol Ecol. 2017 Jun;26(12):3230-3240
pubmed: 28027420
J Am Geriatr Soc. 2014 Feb;62(2):222-9
pubmed: 24428184
Lancet Oncol. 2008 Nov;9(11):1048-57
pubmed: 18799354
Physiol Rev. 2008 Apr;88(2):557-79
pubmed: 18391173
Arch Gynecol Obstet. 2019 Nov;300(5):1413-1421
pubmed: 31549221
Cell. 1989 Dec 1;59(5):871-80
pubmed: 2590943
Lancet. 2007 Jan 13;369(9556):107-14
pubmed: 17223473
PLoS One. 2021 Nov 15;16(11):e0259952
pubmed: 34780545
PLoS One. 2014 Feb 24;9(2):e89828
pubmed: 24587065
Mech Ageing Dev. 2012 Jun;133(6):373-7
pubmed: 22561920
Free Radic Biol Med. 2000 Dec;29(11):1106-14
pubmed: 11121717
Adv Exp Med Biol. 2017;1043:9-27
pubmed: 29224088
J Clin Endocrinol Metab. 2011 Apr;96(4):885-93
pubmed: 21474685
Cell. 2001 Sep 21;106(6):661-73
pubmed: 11572773
Exp Gerontol. 2014 Mar;51:15-27
pubmed: 24365661
Am J Clin Nutr. 2009 Jun;89(6):1721-2
pubmed: 19386739
Photochem Photobiol. 2019 Jan;95(1):244-251
pubmed: 29679477
Redox Biol. 2020 Apr;31:101488
pubmed: 32201219
Exp Gerontol. 2021 Apr;146:111212
pubmed: 33387607
Maturitas. 2015 Oct;82(2):215-21
pubmed: 26297686
Antioxidants (Basel). 2019 Jul 22;8(7):
pubmed: 31336672
Curr Pharm Des. 2009;15(26):3078-90
pubmed: 19754382
Inflamm Bowel Dis. 2009 Sep;15(9):1432-3
pubmed: 19226514
Ageing Res Rev. 2015 Jul;22:72-80
pubmed: 25956165
Molecules. 2019 Aug 24;24(17):
pubmed: 31450559
Clin Nutr. 2015 Aug;34(4):694-9
pubmed: 25131600
Eur J Prev Cardiol. 2014 Jul;21(7):884-91
pubmed: 23253745
Nat Med. 2006 Oct;12(10):1133-8
pubmed: 17024208
Antioxidants (Basel). 2021 Jan 11;10(1):
pubmed: 33440881
Indian J Psychiatry. 2020 Nov-Dec;62(6):678-683
pubmed: 33896973
Sci Am. 1996 Feb;274(2):92-7
pubmed: 8560215
Eur Heart J. 2019 Jan 1;40(1):34-46
pubmed: 30496493
Environ Toxicol Pharmacol. 2015 Nov;40(3):931-5
pubmed: 26513689
Ann Med. 2012 Jun;44 Suppl 1:S138-42
pubmed: 22713142
Nature. 2000 Nov 2;408(6808):53-6
pubmed: 11081503