Long-Term Effects of Biliverdin Reductase a Deficiency in

Crigler-Najjar Gilbert Prdx2 aging fetus iron accumulation triglycerides

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
20 Dec 2021
Historique:
received: 11 10 2021
revised: 07 12 2021
accepted: 15 12 2021
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: epublish

Résumé

Accumulation of neurotoxic bilirubin due to a transient neonatal or persistent inherited deficiency of bilirubin glucuronidation activity can cause irreversible brain damage and death. Strategies to inhibit bilirubin production and prevent neurotoxicity in neonatal and adult settings seem promising. We evaluated the impact of

Identifiants

pubmed: 34943131
pii: antiox10122029
doi: 10.3390/antiox10122029
pmc: PMC8698966
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Giulia Bortolussi (G)

International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.

Xiaoxia Shi (X)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Key Laboratory of Protein Modification and Disease, School of Bioengineering, Dalian University of Technology, Dalian 116024, China.

Lysbeth Ten Bloemendaal (L)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Bhaswati Banerjee (B)

International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.

Dirk R De Waart (DR)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Gabriele Baj (G)

Light Microscopy Imaging Center, Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.

Weiyu Chen (W)

Heart Research Institute, Sydney, NSW 2042, Australia.

Ronald P Oude Elferink (RP)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Ulrich Beuers (U)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Coen C Paulusma (CC)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Roland Stocker (R)

Heart Research Institute, Sydney, NSW 2042, Australia.

Andrés F Muro (AF)

International Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.

Piter J Bosma (PJ)

Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Classifications MeSH