Analysis of Plant Origin Antibiotics against Oral Bacterial Infections Using In Vitro and In Silico Techniques and Characterization of Active Constituents.

Ayurveda biofilm dental plaque diabetes mellitus medicinal plants oral cavity quorum-sensing

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
08 Dec 2021
Historique:
received: 21 10 2021
revised: 23 11 2021
accepted: 25 11 2021
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: epublish

Résumé

The pervasiveness of oral bacterial infections in diabetic patients is a serious health concern that may produce severe complications. We investigated 26 Ayurvedic medicinal plants traditionally used for treatment of the oral bacterial infections with the aim to look for new promising drug leads that can be further employed for herbal formulation design. The plants were grouped into three categories based on traditional usage. All plant extracts were examined for antibacterial, antibiofilm and antiquorum-sensing properties. The plants with significant activities including

Identifiants

pubmed: 34943716
pii: antibiotics10121504
doi: 10.3390/antibiotics10121504
pmc: PMC8699006
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Society for Medicinal Plants Research, Germany
ID : 1234

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Auteurs

Abdul Rafey (A)

NPRL, Gomal Centre of Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, Dera Ismail Khan 29050, Pakistan.

Adnan Amin (A)

NPRL, Gomal Centre of Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, Dera Ismail Khan 29050, Pakistan.

Muhammad Kamran (M)

NPRL, Gomal Centre of Pharmaceutical Sciences, Faculty of Pharmacy, Gomal University, Dera Ismail Khan 29050, Pakistan.

Uzma Haroon (U)

Department of Dentistry, D.H.Q Teaching Hospital, Dera Ismail Khan 29050, Pakistan.

Kainat Farooq (K)

Sardar Begum Dental College, Ghandhara University, Peshawar 25000, Pakistan.

Kenn Foubert (K)

Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

Luc Pieters (L)

Natural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

Classifications MeSH