Parkin beyond Parkinson's Disease-A Functional Meaning of Parkin Downregulation in TDP-43 Proteinopathies.
Parkinson’s disease (PD)
TDP-43 pathology
amyotrophic lateral sclerosis (ALS)
fronto-temporal lobar degeneration (FTLD)
mitophagy
parkin
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
01 12 2021
01 12 2021
Historique:
received:
27
10
2021
revised:
27
11
2021
accepted:
29
11
2021
entrez:
24
12
2021
pubmed:
25
12
2021
medline:
7
1
2022
Statut:
epublish
Résumé
Parkin and PINK1 are key regulators of mitophagy, an autophagic pathway for selective elimination of dysfunctional mitochondria. To this date, parkin depletion has been associated with recessive early onset Parkinson's disease (PD) caused by loss-of-function mutations in the
Identifiants
pubmed: 34943897
pii: cells10123389
doi: 10.3390/cells10123389
pmc: PMC8699658
pii:
doi:
Substances chimiques
Ubiquitin-Protein Ligases
EC 2.3.2.27
parkin protein
EC 2.3.2.27
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Structure. 2016 Sep 6;24(9):1537-49
pubmed: 27545621
Cell Rep. 2020 Jan 21;30(3):687-698.e6
pubmed: 31968246
Biomedicines. 2021 Apr 02;9(4):
pubmed: 33918437
Int Rev Neurobiol. 2019;149:249-275
pubmed: 31779815
J Mov Disord. 2013 May;6(1):1-8
pubmed: 24868417
Parkinsonism Relat Disord. 2015 Jul;21(7):717-22
pubmed: 25960264
J Exp Med. 2017 Sep 4;214(9):2611-2628
pubmed: 28778989
Lancet Neurol. 2007 Jul;6(7):652-62
pubmed: 17582365
Arch Neurol. 2008 Apr;65(4):460-4
pubmed: 18413467
PLoS Biol. 2016 Apr 20;14(4):e1002447
pubmed: 27096426
Int J Mol Sci. 2020 Apr 24;21(8):
pubmed: 32344772
J Biol Chem. 2009 Mar 27;284(13):8516-24
pubmed: 19164285
J Mol Neurosci. 2011 Nov;45(3):343-9
pubmed: 21892619
Int J Mol Sci. 2018 Dec 20;20(1):
pubmed: 30577465
EMBO J. 2017 Oct 16;36(20):2931-2950
pubmed: 28916614
Brain. 2018 Feb 1;141(2):521-534
pubmed: 29253099
J Neurochem. 2016 Aug;138 Suppl 1:32-53
pubmed: 27009575
Ann Neurol. 2001 Mar;49(3):367-76
pubmed: 11261512
Sci Rep. 2017 Mar 10;7:44373
pubmed: 28281653
Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):153-174
pubmed: 28054827
Nat Rev Mol Cell Biol. 2011 Jan;12(1):9-14
pubmed: 21179058
Front Mol Neurosci. 2019 Dec 17;12:301
pubmed: 31920533
J Mol Neurosci. 2011 Nov;45(3):336-42
pubmed: 21887521
Cell. 2020 Oct 29;183(3):636-649.e18
pubmed: 33031745
Neuron. 2016 Oct 19;92(2):383-391
pubmed: 27720481
PLoS One. 2014 Jan 30;9(1):e86720
pubmed: 24497973
Mov Disord. 1998 Nov;13(6):885-94
pubmed: 9827611
Neurobiol Aging. 2019 Jun;78:98-110
pubmed: 30925302
Neurobiol Aging. 2021 Nov;107:168-173
pubmed: 34175147
Brain. 2020 Oct 1;143(10):3041-3051
pubmed: 33029617
Cell Death Dis. 2018 Sep 20;9(10):953
pubmed: 30237395
Neural Regen Res. 2020 Sep;15(9):1654-1655
pubmed: 32209766
Neurobiol Aging. 2020 Jul;91:168.e1-168.e5
pubmed: 32249012
Acta Neuropathol. 2013 Dec;126(6):859-79
pubmed: 24096617
J Cell Biol. 2010 Dec 27;191(7):1225-7
pubmed: 21187326
Acta Neuropathol. 2021 Feb;141(2):257-279
pubmed: 33398403
Mov Disord. 2017 Nov;32(11):1504-1523
pubmed: 29124790
Neuropathology. 2018 Feb;38(1):98-107
pubmed: 29063640
Neuron. 2011 Sep 22;71(6):1030-42
pubmed: 21943601
Front Aging Neurosci. 2016 Jan 12;7:248
pubmed: 26793099
Brain Res. 2012 Jun 26;1462:40-3
pubmed: 22261247
Neuron. 2013 Aug 7;79(3):416-38
pubmed: 23931993
Mol Neurodegener. 2020 Mar 13;15(1):20
pubmed: 32169097
PLoS One. 2012;7(5):e37057
pubmed: 22623979
Biochem Biophys Res Commun. 2006 Dec 22;351(3):602-11
pubmed: 17084815
Am J Pathol. 2012 Jan;180(1):293-302
pubmed: 22067910
J Neurol Neurosurg Psychiatry. 2011 May;82(5):476-86
pubmed: 20971753
J Virol. 1995 Jun;69(6):3584-96
pubmed: 7745706
Nat Commun. 2018 Jul 20;9(1):2845
pubmed: 30030424
Neurobiol Aging. 2009 May;30(5):739-51
pubmed: 17949857
J Neuropathol Exp Neurol. 2018 Jul 1;77(7):608-627
pubmed: 29788265
Parkinsonism Relat Disord. 2013 Mar;19(3):312-5
pubmed: 23231971
Brain. 2019 Dec 1;142(12):3771-3790
pubmed: 31647549
Adv Exp Med Biol. 2021;1281:243-267
pubmed: 33433879
Trends Mol Med. 2014 Feb;20(2):66-71
pubmed: 24355761
Nat Commun. 2019 Sep 13;10(1):4162
pubmed: 31519910
Biochim Biophys Acta. 2011 Aug;1812(8):1041-53
pubmed: 21215313
PLoS One. 2016 Apr 21;11(4):e0153852
pubmed: 27100392
Cell Mol Life Sci. 2021 Apr;78(8):3853-3866
pubmed: 33782711
Acta Neurobiol Exp (Wars). 2013;73(2):199-224
pubmed: 23823983
Hum Mol Genet. 2018 May 1;27(9):1593-1607
pubmed: 29474575
Brain. 2017 Jan;140(1):98-117
pubmed: 27807026
Cell Rep. 2020 Aug 4;32(5):107989
pubmed: 32755582
Neuron. 2019 Mar 20;101(6):1057-1069
pubmed: 30897357
FEBS J. 2016 Apr;283(7):1242-60
pubmed: 26756435
J Biol Chem. 2001 Sep 28;276(39):36337-43
pubmed: 11470789
PLoS Genet. 2019 May 17;15(5):e1007947
pubmed: 31100073
Neuron. 2015 Jan 21;85(2):257-73
pubmed: 25611507
Acta Neuropathol. 2007 Jul;114(1):49-54
pubmed: 17458552
Mol Cell Neurosci. 2019 Oct;100:103396
pubmed: 31445085
Neuropathol Appl Neurobiol. 2019 Feb;45(1):41-57
pubmed: 30575981
Neurosci Insights. 2020 Sep 17;15:2633105520957302
pubmed: 32995749
Transl Neurodegener. 2019 Sep 4;8:28
pubmed: 31508228
Mov Disord. 2009 Nov 15;24(15):2260-6
pubmed: 19845000
Brain Pathol. 2017 Nov;27(6):723-736
pubmed: 28100023
Cell Death Dis. 2020 Nov 5;11(11):952
pubmed: 33154354
Exp Neurol. 2014 Dec;262 Pt B:75-83
pubmed: 24246281
Neurobiol Dis. 2021 Jul;154:105359
pubmed: 33798740
J Biol Chem. 2019 Apr 19;294(16):6306-6317
pubmed: 30814253
Neurosci Lett. 2002 Apr 19;323(1):50-4
pubmed: 11911988
EMBO Mol Med. 2013 Aug;5(8):1247-62
pubmed: 23737459
Brain. 1996 Dec;119 ( Pt 6):2097-103
pubmed: 9010013
Hum Mol Genet. 2011 Mar 1;20(5):867-79
pubmed: 21138942
Acta Neuropathol Commun. 2020 Jul 24;8(1):116
pubmed: 32709255
J Alzheimers Dis. 2014;38(4):747-52
pubmed: 24064467
Front Mol Neurosci. 2019 Feb 14;12:25
pubmed: 30837838
Neurosci Lett. 2019 Apr 1;697:34-48
pubmed: 29626651
Neurobiol Dis. 2021 Jul;154:105360
pubmed: 33812000
Int J Mol Sci. 2021 Sep 24;22(19):
pubmed: 34638637
Curr Opin Genet Dev. 2017 Jun;44:47-53
pubmed: 28213158
Ann Neurol. 1997 Jun;41(6):706-15
pubmed: 9189031
Neurology. 2011 Mar 15;76(11):1006-14
pubmed: 21325651
N Engl J Med. 2000 May 25;342(21):1560-7
pubmed: 10824074
Lancet Neurol. 2020 Feb;19(2):170-178
pubmed: 31521533
Front Cell Dev Biol. 2020 Jun 11;8:423
pubmed: 32596240
Nat Neurosci. 2011 Apr;14(4):459-68
pubmed: 21358643
J Cell Biol. 2008 Dec 1;183(5):795-803
pubmed: 19029340
Curr Opin Cell Biol. 2015 Apr;33:95-101
pubmed: 25697963
Neurosci Lett. 2012 Nov 21;530(2):144-9
pubmed: 23063673
Trends Genet. 2018 Jun;34(6):404-423
pubmed: 29605155
Hum Mol Genet. 2010 Jan 15;19(2):313-28
pubmed: 19864493
Autophagy. 2021 May 31;:1-29
pubmed: 34057020
PLoS One. 2010 Sep 27;5(9):e12962
pubmed: 20885945
Front Mol Neurosci. 2021 May 13;14:676478
pubmed: 34054428
Nat Rev Neurol. 2016 Mar;12(3):175-85
pubmed: 26891767
Neurobiol Dis. 2018 Jul;115:167-181
pubmed: 29630989
Eur J Neurol. 2021 Dec;28(12):4010-4021
pubmed: 34342072
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18619-24
pubmed: 25503365
Brain. 2006 Nov;129(Pt 11):3103-14
pubmed: 17030535
Parkinsonism Relat Disord. 2018 Oct;55:145-147
pubmed: 29910155
J Neurol Neurosurg Psychiatry. 2020 Nov 11;:
pubmed: 33177049
Neurosci Lett. 2019 Jul 13;705:7-13
pubmed: 30995519
PLoS Biol. 2021 Apr 28;19(4):e3001198
pubmed: 33909608
Acta Neuropathol. 2012 Sep;124(3):325-38
pubmed: 22806825
Parkinsonism Relat Disord. 2014 Sep;20(9):957-64
pubmed: 24998994
Hum Mol Genet. 2014 Sep 15;23(18):4960-9
pubmed: 24847002
Cell Death Dis. 2019 Jul 8;10(7):524
pubmed: 31285425
Neurosci Lett. 2018 Jun 21;678:8-15
pubmed: 29715546
PLoS One. 2012;7(6):e38658
pubmed: 22761693
Parkinsonism Relat Disord. 2020 Aug;77:114-120
pubmed: 32717578
Brain. 2003 Jun;126(Pt 6):1279-92
pubmed: 12764051
Cells. 2021 Jan 15;10(1):
pubmed: 33467748
Hum Mol Genet. 2016 Jun 15;25(12):2378-2392
pubmed: 27056981
Int J Med Sci. 2021 Jan 1;18(2):378-386
pubmed: 33390807
Ageing Res Rev. 2018 Mar;42:72-85
pubmed: 29288112
Front Mol Neurosci. 2017 May 30;10:170
pubmed: 28611593
EMBO J. 2021 Feb 1;40(3):e104705
pubmed: 33438778
Neurology. 2009 Mar 24;72(12):1041-7
pubmed: 19038850
Acta Neuropathol Commun. 2016 May 05;4(1):47
pubmed: 27151080
Neuropathol Appl Neurobiol. 2016 Apr;42(3):217-9
pubmed: 26577056
Front Aging Neurosci. 2015 Sep 01;7:171
pubmed: 26388768
Acta Neuropathol. 2019 Jan;137(1):47-69
pubmed: 30450515
Nature. 1998 Apr 9;392(6676):605-8
pubmed: 9560156
Neurology. 2005 Jan 11;64(1):134-6
pubmed: 15642918
Nat Rev Neurol. 2018 Sep;14(9):544-558
pubmed: 30120348
Cell Cycle. 2021 Apr;20(7):631-646
pubmed: 33722167
Nat Neurosci. 2019 Jun;22(6):851-862
pubmed: 31086314
Stem Cells. 2016 Aug;34(8):2063-78
pubmed: 27097283
J Mol Med (Berl). 2014 Apr;92(4):373-86
pubmed: 24337465
J Biol Chem. 2014 Apr 11;289(15):10769-10784
pubmed: 24515116
Brain. 2012 Apr;135(Pt 4):1128-40
pubmed: 22434215
J Neurochem. 2011 Jun;117(5):856-67
pubmed: 21426348
Cold Spring Harb Perspect Med. 2012 Jan;2(1):a008888
pubmed: 22315721
Nat Neurosci. 2012 Nov;15(11):1488-97
pubmed: 23023293
Parkinsonism Relat Disord. 2009 Jul;15(6):425-9
pubmed: 19162522
Cell Res. 2021 Apr;31(4):379-380
pubmed: 33603118
Stem Cell Reports. 2020 May 12;14(5):892-908
pubmed: 32330447
Science. 2004 May 21;304(5674):1158-60
pubmed: 15087508
Sci Data. 2019 Feb 05;6:190006
pubmed: 30720798
Nature. 2006 Aug 24;442(7105):916-9
pubmed: 16862116
Chimia (Aarau). 2019 May 29;73(6):380-390
pubmed: 31118120
Neurol Genet. 2021 Mar 12;7(2):e575
pubmed: 33977144
Hum Mol Genet. 2014 May 1;23(9):2298-312
pubmed: 24334610
Cell Rep. 2017 Sep 12;20(11):2565-2574
pubmed: 28903038
Curr Biol. 2018 Feb 19;28(4):R170-R185
pubmed: 29462587
Acta Neuropathol. 2012 Nov;124(5):717-32
pubmed: 22993125
Nat Neurosci. 2019 Feb;22(2):167-179
pubmed: 30643292
Nature. 2016 Nov 10;539(7628):197-206
pubmed: 27830784
Neurodegener Dis. 2014;13(2-3):69-71
pubmed: 24029689
Nat Struct Mol Biol. 2021 Feb;28(2):132-142
pubmed: 33398173
Front Neurosci. 2019 Apr 11;13:335
pubmed: 31031584
Front Cell Neurosci. 2021 Apr 01;15:653688
pubmed: 33867942
Neurology. 2005 Jun 14;64(11):1958-60
pubmed: 15955954
Prog Neurobiol. 2019 Jun;177:73-93
pubmed: 30219247
J Biol Chem. 2009 Jul 24;284(30):20329-39
pubmed: 19465477
Exp Neurol. 2021 May;339:113620
pubmed: 33497646
Nat Struct Mol Biol. 2013 Dec;20(12):1443-9
pubmed: 24240615
Expert Opin Ther Targets. 2018 Mar;22(3):279-293
pubmed: 29431050
Acta Neuropathol. 2017 Jul;134(1):79-96
pubmed: 28466142
Cell Metab. 2021 Mar 2;33(3):531-546.e9
pubmed: 33545050
Brain. 2015 Oct;138(Pt 10):3110-22
pubmed: 26231953
Dis Model Mech. 2019 Aug 16;12(8):
pubmed: 31439573
Brain. 2005 Oct;128(Pt 10):2281-90
pubmed: 15947065
Acta Neuropathol. 2018 Jul;136(1):1-17
pubmed: 29744576
Nat Commun. 2014 Sep 12;5:4824
pubmed: 25215604
Cells. 2019 Jul 12;8(7):
pubmed: 31336937
J Biol Chem. 2013 Feb 8;288(6):4103-15
pubmed: 23258539
Biomedicines. 2021 May 25;9(6):
pubmed: 34070550
Nat Commun. 2017 Jun 29;8(1):45
pubmed: 28663553
Ann Neurol. 2008 Nov;64(5):555-65
pubmed: 19067348
Science. 2016 Jan 8;351(6269):173-6
pubmed: 26634439
Neuropathol Appl Neurobiol. 2019 Feb;45(1):58-80
pubmed: 30582188
Science. 2006 Oct 6;314(5796):130-3
pubmed: 17023659
Transl Neurodegener. 2020 Oct 30;9(1):40
pubmed: 33126923
Neurobiol Dis. 2019 Apr;124:230-239
pubmed: 30448284
Autophagy. 2013 Nov 1;9(11):1758-69
pubmed: 24121706
Acta Neuropathol Commun. 2020 Oct 7;8(1):163
pubmed: 33028409