ATPase Activity of the Subcellular Fractions of Colorectal Cancer Samples under the Action of Nicotinic Acid Adenine Dinucleotide Phosphate.

ATPase Ca2+ Ca2+ ATPase Ca2+ ATPase PM EPR NAADP Na+/K+ ATPase acidic store autophagy basal ATPase activity cancer

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
30 Nov 2021
Historique:
received: 21 10 2021
revised: 23 11 2021
accepted: 29 11 2021
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: epublish

Résumé

In tumor cells with defects in apoptosis, autophagy allows prolonged survival. Autophagy leads to an accumulation of damaged mitochondria by autophagosomes. An acidic environment is maintained in compartments of cells, such as autophagosomes, late endosomes, and lysosomes; these organelles belong to the "acid store" of the cells. Nicotinic acid adenine dinucleotide phosphate (NAADP) may affect the release of Ca

Identifiants

pubmed: 34944620
pii: biomedicines9121805
doi: 10.3390/biomedicines9121805
pmc: PMC8698369
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Masaryk University
ID : MUNI/A/1425/2020

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Auteurs

Ivan Kushkevych (I)

Department of Experimental Biology, Faculty of Science, Masaryk University, 62500 Brno, Czech Republic.

Mykola Bychkov (M)

Department of Therapy No 1, Medical Diagnostic and Hematology and Transfusiology of Faculty of Postgraduate Education, Danylo Halytsky Lviv National Medical University, 79010 Lviv, Ukraine.

Solomiia Bychkova (S)

Department of Human and Animal Physiology, Faculty of Biology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.

Márió Gajdács (M)

Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, 6720 Szeged, Hungary.
Faculty of Medicine, Institute of Medical Microbiology, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, Hungary.

Romana Merza (R)

Department of Anesthesiology and Intensive Care, Faculty of Postgraduate Education, Danylo Halytsky Lviv National Medical University, 79010 Lviv, Ukraine.

Monika Vítězová (M)

Department of Experimental Biology, Faculty of Science, Masaryk University, 62500 Brno, Czech Republic.

Classifications MeSH