Skin Wound Healing of the Adult Newt,

color pattern newt re-epithelialization scarless skin regeneration

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
13 Dec 2021
Historique:
received: 26 11 2021
revised: 10 12 2021
accepted: 11 12 2021
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: epublish

Résumé

In surgical and cosmetic studies, scarless regeneration is an ideal method to heal skin wounds. To study the technologies that enable scarless skin wound healing in medicine, animal models are useful. However, four-limbed vertebrates, including humans, generally lose their competency of scarless regeneration as they transit to their terrestrial life-stages through metamorphosis, hatching or birth. Therefore, animals that serve as a model for postnatal humans must be an exception to this rule, such as the newt. Here, we evaluated the adult newt in detail for the first time. Using a Japanese fire-bellied newt,

Identifiants

pubmed: 34944708
pii: biomedicines9121892
doi: 10.3390/biomedicines9121892
pmc: PMC8698868
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministry of Education, Culture, Sports, Science and Technology
ID : 221S0002
Organisme : Japan Society for the Promotion of Science
ID : 18H04061

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Auteurs

Tatsuyuki Ishii (T)

Department of Plastic and Reconstructive Surgery, Keio University, Shinanomachi 35, Tokyo 160-8582, Japan.

Ikkei Takashimizu (I)

Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

Martin Miguel Casco-Robles (MM)

Faculty of Life and Environmental Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8572, Japan.

Yuji Taya (Y)

Department of Pathology, The Nippon Dental University School of Life Dentistry at Tokyo, Fujimi 1-9-20, Tokyo 102-8159, Japan.

Shunsuke Yuzuriha (S)

Department of Plastic and Reconstructive Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390-8621, Japan.

Fubito Toyama (F)

Graduate School of Engineering, Utsunomiya University, Yoto 7-1-2, Utsunomiya 321-8585, Japan.

Fumiaki Maruo (F)

Faculty of Life and Environmental Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8572, Japan.

Kazuo Kishi (K)

Department of Plastic and Reconstructive Surgery, Keio University, Shinanomachi 35, Tokyo 160-8582, Japan.

Chikafumi Chiba (C)

Faculty of Life and Environmental Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8572, Japan.

Classifications MeSH