Multicenter Technical Validation of 30 Rapid Antigen Tests for the Detection of SARS-CoV-2 (VALIDATE).

COVID-19 SARS-CoV-2 diagnostics rapid antigen test virus testing

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
15 Dec 2021
Historique:
received: 08 11 2021
revised: 02 12 2021
accepted: 04 12 2021
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: epublish

Résumé

During COVID19 pandemic, SARS-CoV-2 rapid antigen tests (RATs) were marketed with minimal or no performance data. We aimed at closing this gap by determining technical sensitivities and specificities of 30 RATs prior to market release. We developed a standardized technical validation protocol and assessed 30 RATs across four diagnostic laboratories. RATs were tested in parallel using the Standard Q

Identifiants

pubmed: 34946190
pii: microorganisms9122589
doi: 10.3390/microorganisms9122589
pmc: PMC8704317
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Gilbert Greub (G)

Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
Infectious Diseases Service, Department of Internal Medicine, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
Coordination Commission of Clinical Microbiology, Swiss Society of Microbiology, 1033 Cheseaux, Switzerland.

Giorgia Caruana (G)

Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.

Michael Schweitzer (M)

Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
Applied Microbiology Research, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Mauro Imperiali (M)

Centro Medicina di Laboratorio Dr Risch, Via Arbostra 2, 6963 Pregassona, Switzerland.

Veronika Muigg (V)

Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.

Martin Risch (M)

Coordination Commission of Clinical Microbiology, Swiss Society of Microbiology, 1033 Cheseaux, Switzerland.
Centro Medicina di Laboratorio Dr Risch, Via Arbostra 2, 6963 Pregassona, Switzerland.

Antony Croxatto (A)

Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
ADMed Microbiologie Laboratory, 2300 La Chaux-de-Fonds, Switzerland.

Onya Opota (O)

Institute of Microbiology, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.

Stefanie Heller (S)

Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
Applied Microbiology Research, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Diana Albertos Torres (D)

Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
Applied Microbiology Research, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Marie-Lise Tritten (ML)

ADMed Microbiologie Laboratory, 2300 La Chaux-de-Fonds, Switzerland.

Karoline Leuzinger (K)

Clinical Virology, University Hospital Basel, 4031 Basel, Switzerland.
Transplantation & Clinical Virology, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.

Hans H Hirsch (HH)

Clinical Virology, University Hospital Basel, 4031 Basel, Switzerland.
Transplantation & Clinical Virology, Department of Biomedicine, University of Basel, 4031 Basel, Switzerland.
Infectious Diseases and Hospital Epidemiology, University Hospital Basel, 4031 Basel, Switzerland.

Reto Lienhard (R)

Coordination Commission of Clinical Microbiology, Swiss Society of Microbiology, 1033 Cheseaux, Switzerland.
ADMed Microbiologie Laboratory, 2300 La Chaux-de-Fonds, Switzerland.

Adrian Egli (A)

Coordination Commission of Clinical Microbiology, Swiss Society of Microbiology, 1033 Cheseaux, Switzerland.
Clinical Bacteriology and Mycology, University Hospital Basel, 4031 Basel, Switzerland.
Clinical Virology, University Hospital Basel, 4031 Basel, Switzerland.

Classifications MeSH