Journal

HGG advances
ISSN: 2666-2477
Titre abrégé: HGG Adv
Pays: United States
ID NLM: 101772885

Informations de publication

Date de publication:
14 Oct 2021
Historique:
entrez: 24 12 2021
pubmed: 25 12 2021
medline: 25 12 2021
Statut: ppublish

Résumé

Xia-Gibbs syndrome (XGS; MIM: 615829) is a phenotypically heterogeneous neurodevelopmental disorder (NDD) caused by newly arising mutations in the AT-Hook DNA-Binding Motif-Containing 1 (

Identifiants

pubmed: 34950897
doi: 10.1016/j.xhgg.2021.100049
pmc: PMC8694554
mid: NIHMS1762851
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NHGRI NIH HHS
ID : K08 HG008986
Pays : United States
Organisme : NINDS NIH HHS
ID : R35 NS105078
Pays : United States
Organisme : NHGRI NIH HHS
ID : U01 HG011758
Pays : United States
Organisme : NHGRI NIH HHS
ID : UM1 HG008898
Pays : United States

Déclaration de conflit d'intérêts

Declaration of interests J.R.L. has stock ownership in 23andMe, is a paid consultant for the Regeneron Genetics Center, and is a coinventor on multiple US and European patents related to molecular diagnostics for inherited neuropathies, eye diseases, and bacterial genomic fingerprinting. The Department of Molecular and Human Genetics at Baylor College of Medicine derives revenue from the chromosomal microarray analysis (CMA) and clinical exome sequencing (cES) offered in the Baylor Genetics (BG) Laboratory. J.R.L. serves on the Scientific Advisory Board of BG. J.F.’s spouse is Founder and Principal of Friedman Bioventure, which holds a variety of publicly traded and private biotechnology interests. K.M. is an employee of GeneDx, Inc. All other authors declare no competing interests.

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Auteurs

Michael M Khayat (MM)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
These authors contributed equally to this work.

Jianhong Hu (J)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
These authors contributed equally to this work.

Yunyun Jiang (Y)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
These authors contributed equally to this work.

He Li (H)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.

Varuna Chander (V)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Moez Dawood (M)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.

Adam W Hansen (AW)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Shoudong Li (S)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.

Jennifer Friedman (J)

UCSD Departments of Neuroscience and Pediatrics, Rady Children's Hospital Division of Neurology, Rady Children's Institute for Genomic Medicine, San Diego, CA, USA.

Laura Cross (L)

Department of Pediatrics and Genetics, Children's Mercy Hospitals, Kansas City, MO, USA.

Emilia K Bijlsma (EK)

Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.

Claudia A L Ruivenkamp (CAL)

Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.

Francis H Sansbury (FH)

All Wales Medical Genomics Service, NHS Wales Cardiff and Vale University Health Board, Institute of Medical Genetics, University Hospital of Wales, Cardiff, UK.

Jeffrey W Innis (JW)

Departments of Human Genetics, Pediatrics, and Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

Jessica Omark O'Shea (JO)

Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.

Qingchang Meng (Q)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.

Jill A Rosenfeld (JA)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Kirsty McWalter (K)

GeneDx, Gaithersburg, MD, USA.

Michael F Wangler (MF)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Texas Children's Neurological Research Institute, Houston, TX, USA.

James R Lupski (JR)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Texas Children's Hospital, Houston, TX, USA.
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

Jennifer E Posey (JE)

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

David Murdock (D)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Richard A Gibbs (RA)

Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Classifications MeSH