Redox balance in human skeletal muscle-derived endothelial cells - Effect of exercise training.
Mitochondria
Physical activity
Reactive oxygen species
Respirometry
Vascular function
Journal
Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159
Informations de publication
Date de publication:
01 02 2022
01 02 2022
Historique:
received:
25
10
2021
revised:
12
12
2021
accepted:
16
12
2021
pubmed:
27
12
2021
medline:
1
2
2022
entrez:
26
12
2021
Statut:
ppublish
Résumé
Aerobic training can improve vascular endothelial function in-vivo. The aim of this study was to elucidate the mechanisms underlying this improvement in isolated human microvascular endothelial cells. Sedentary males, aged 57 ± 6 years completed 8 weeks of intense aerobic training. Resting muscle biopsies were obtained from the thigh muscle and used for isolation of endothelial cells (pre n = 23, post n = 16). The cells were analyzed for mitochondrial respiration, H
Identifiants
pubmed: 34954023
pii: S0891-5849(21)01117-5
doi: 10.1016/j.freeradbiomed.2021.12.265
pii:
doi:
Substances chimiques
Hydrogen Peroxide
BBX060AN9V
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
144-155Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.