NFAT5 Controls the Integrity of Epidermis.

Animals Cell Differentiation / physiology Epidermis / anatomy & histology Keratinocytes / cytology Mice Mice, Inbred C57BL Mice, Knockout NFATC Transcription Factors / metabolism
Mmp3 NFAT5 epidermis kallikrein 7 keratinocytes matrix proteases skin

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2021
Historique:
received: 21 09 2021
accepted: 15 11 2021
entrez: 27 12 2021
pubmed: 28 12 2021
medline: 15 2 2022
Statut: epublish

Résumé

The skin protects the human body against dehydration and harmful challenges. Keratinocytes (KCs) are the most abundant epidermal cells, and it is anticipated that KC-mediated transport of Na

Identifiants

DOI: 10.3389/fimmu.2021.780727 PMID: 34956208 PMC: PMC8696207
pubmed: 34956208
doi: 10.3389/fimmu.2021.780727
pmc: PMC8696207
doi:

Substances chimiques

NFATC Transcription Factors 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

780727

Informations de copyright

Copyright © 2021 Muhammad, Xavier, Klein-Hessling, Azeem, Rauschenberger, Murti, Avots, Goebeler, Klein, Bopp, Sielaff, Tenzer, Möckel, Aramburu, López-Rodríguez, Kerstan and Serfling.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Khalid Muhammad (K)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.

Delicia Xavier (D)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.

Stefan Klein-Hessling (S)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.
Comprehensive Cancer Centre Mainfranken, Wuerzburg, Germany.

Muhammad Azeem (M)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.
Department of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, Wuerzburg, Germany.

Tabea Rauschenberger (T)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.

Krisna Murti (K)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.

Andris Avots (A)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.
Comprehensive Cancer Centre Mainfranken, Wuerzburg, Germany.

Matthias Goebeler (M)

Department of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, Wuerzburg, Germany.

Matthias Klein (M)

Institute for Immunology, University Medical Center, University of Mainz, Mainz, Germany.

Tobias Bopp (T)

Institute for Immunology, University Medical Center, University of Mainz, Mainz, Germany.
Research Center for Immunotherapy, University Medical Center, University of Mainz, Mainz, Germany.
University Cancer Center Mainz, University Medical Center, University of Mainz, Mainz, Germany.

Malte Sielaff (M)

Institute for Immunology, University Medical Center, University of Mainz, Mainz, Germany.

Stefan Tenzer (S)

Institute for Immunology, University Medical Center, University of Mainz, Mainz, Germany.

Sigrid Möckel (S)

Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.

José Aramburu (J)

Immunology Unit, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

Cristina López-Rodríguez (C)

Immunology Unit, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

Andreas Kerstan (A)

Department of Dermatology, Venereology and Allergology, University Hospital Wuerzburg, Wuerzburg, Germany.

Edgar Serfling (E)

Department of Molecular Pathology, Institute of Pathology, University of Wuerzburg, Wuerzburg, Germany.
Comprehensive Cancer Centre Mainfranken, Wuerzburg, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Système tégumentaire › Peau › Épiderme › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Cellules › Cellules épithéliales › Kératinocytes › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › NFAT5 Controls the Integrity of Epidermis.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription NFATC › NFAT5 Controls the Integrity of Epidermis.