Retrospective audit of antibiotic use in a university general pediatrics department using hospital pharmacy dispensing data.

antibiotic stewardship antibiotic use general pediatrics neonatal and pediatric intensive care unit (NPICU) pharmacy dispensing data

Journal

GMS infectious diseases
ISSN: 2195-8831
Titre abrégé: GMS Infect Dis
Pays: Germany
ID NLM: 101694381

Informations de publication

Date de publication:
2021
Historique:
entrez: 27 12 2021
pubmed: 28 12 2021
medline: 28 12 2021
Statut: epublish

Résumé

Antibiotics are among the most frequently prescribed drugs in children's hospitals, which is why regular monitoring of antibiotic use in hospitals is of great importance. This retrospective audit (60 months, January 2014 - December 2018) analyzes the antibiotic consumption at a university inpatient department of general pediatrics including neonatal and pediatric intensive care based on pharmacy dispensing data in units of grams per 100 patient days and in Defined Daily Doses per 100 patient days. The results provide potential targets for Antibiotic Stewardship interventions. Conversely, this audit elicits methodological limitations of the method of antibiotic surveillance in pediatrics recommended by the Robert Koch Institute, Berlin.

Identifiants

pubmed: 34956817
doi: 10.3205/id000075
pii: id000075
pmc: PMC8662896
doi:

Types de publication

Journal Article

Langues

eng

Pagination

Doc06

Informations de copyright

Copyright © 2021 Egle et al.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Références

Infect Control Hosp Epidemiol. 2012 Apr;33(4):346-53
pubmed: 22418629
Infect Control Hosp Epidemiol. 2013 Dec;34(12):1252-8
pubmed: 24225609
Arch Dis Child. 2009 Sep;94(9):724-8
pubmed: 19531524
Pediatr Crit Care Med. 2009 Jul;10(4):495-9
pubmed: 19451853
BMJ Open. 2016 Nov 3;6(11):e012675
pubmed: 27810974
J Hosp Infect. 2013 Aug;84(4):300-4
pubmed: 23831281
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Jul;56(7):996-1002
pubmed: 23807408
PLoS One. 2015 Sep 25;10(9):e0139097
pubmed: 26405817
J Antimicrob Chemother. 2017 Jan;72(1):1-18
pubmed: 27659735
Pediatr Crit Care Med. 2016 Mar;17(3):187-93
pubmed: 26669645
Infection. 2009 Aug;37(4):349-52
pubmed: 19277464
Ther Drug Monit. 2003 Oct;25(5):593-9
pubmed: 14508383
Clin Infect Dis. 2015 May 1;60(9):1389-97
pubmed: 25595742
J Antimicrob Chemother. 2014 Jul;69(7):1748-54
pubmed: 24633207
Infect Dis Clin North Am. 2018 Mar;32(1):1-17
pubmed: 29406971
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Jul;56(7):903-12
pubmed: 23807401
Expert Opin Drug Metab Toxicol. 2009 Jan;5(1):57-69
pubmed: 19236229
Pediatrics. 2010 Dec;126(6):1067-73
pubmed: 21078728
Int J Antimicrob Agents. 2013 Feb;41(2):137-42
pubmed: 23276500
Eur J Pediatr. 2018 Aug;177(8):1271-1278
pubmed: 29948254
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014 Apr;57(4):399-405
pubmed: 24658669
Infection. 2017 Aug;45(4):493-504
pubmed: 28397171
Curr Infect Dis Rep. 2013 Dec;15(6):559-63
pubmed: 24097249
J Pediatric Infect Dis Soc. 2016 Sep;5(3):342-5
pubmed: 26407269
J Pediatric Infect Dis Soc. 2019 May 11;8(2):143-151
pubmed: 29579259

Auteurs

Leonie Egle (L)

Pediatric Hematology and Oncology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Katharina Sauter (K)

Pediatric Hematology and Oncology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Svenja Ockfen (S)

Pediatric Hematology and Oncology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Manfred Haber (M)

Pharmacy, Saarland University Hospital, Homburg/Saar, Germany.

Sören Becker (S)

Center for Infectious Diseases, Institute of Medical Microbiology and Hygiene, Saarland University Hospital, Homburg/Saar, Germany.

Gudrun Wagenpfeil (G)

Institute for Medical Biometry, Epidemiology and Medical Informatics, University Medical Center, Saarland University, Campus Homburg, Homburg, Germany.

Michael Zemlin (M)

Department Clinic for General Pediatrics and Neonatology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Sascha Meyer (S)

Department Clinic for General Pediatrics and Neonatology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Arne Simon (A)

Pediatric Hematology and Oncology, Children's Hospital Medical Center, Saarland University Hospital, Homburg/Saar, Germany.

Classifications MeSH