Altered circulating marinobufagenin levels and recurrent intradialytic hypotensive episodes in chronic hemodialysis patients: a pilot, prospective study.
Hemodialysis
Intradialytic hypotension
Marinobufagenin
Journal
Reviews in cardiovascular medicine
ISSN: 1530-6550
Titre abrégé: Rev Cardiovasc Med
Pays: Singapore
ID NLM: 100960007
Informations de publication
Date de publication:
22 Dec 2021
22 Dec 2021
Historique:
received:
12
07
2021
revised:
21
08
2021
accepted:
10
09
2021
entrez:
27
12
2021
pubmed:
28
12
2021
medline:
24
3
2022
Statut:
ppublish
Résumé
Intradialytic hypotension (IDH) is a sudden and often serious complication of chronic hemodialysis (HD). In this prospective study, we aimed at evaluating the clinical predictors of IDH in a homogeneous cohort of chronic HD patients, with a particular focus on marinobufagenin (MBG), an endogenous cardiotonic steroid which alterations have previously been involved in various cardiovascular disorders. MBG levels in HD patients were significantly higher than in controls (
Identifiants
pubmed: 34957798
pii: S1530-6550(21)00237-4
doi: 10.31083/j.rcm2204163
doi:
Substances chimiques
Bufanolides
0
marinobufagenin
3KBT25GV2B
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1577-1587Informations de copyright
© 2021 The Author(s). Published by IMR Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. Davide Bolignano is serving as one of the Editorial Board members of this journal. We declare that Davide Bolignano had no involvement in the peer review of this article and has no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to Peter A. McCullough.