Dually Cross-Linked Core-Shell Structure Nanohydrogel with Redox-Responsive Degradability for Intracellular Delivery.
cancer immunotherapy
drug delivery system
factor influence study
macromolecule
nanocapsule
peroxidase-like enzymatic activity
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
30 11 2021
30 11 2021
Historique:
received:
20
10
2021
revised:
20
11
2021
accepted:
25
11
2021
entrez:
28
12
2021
pubmed:
29
12
2021
medline:
29
12
2021
Statut:
epublish
Résumé
A redox-responsive nanocarrier is a promising strategy for the intracellular drug release because it protects the payload, prevents its undesirable leakage during extracellular transport, and favors site-specific drug delivery. In this study, we developed a novel redox responsive core-shell structure nanohydrogel prepared by a water in oil nanoemulsion method using two biocompatible synthetic polymers: vinyl sulfonated poly(
Identifiants
pubmed: 34959330
pii: pharmaceutics13122048
doi: 10.3390/pharmaceutics13122048
pmc: PMC8708258
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : European Commission
ID : 675743
Organisme : European Commission
ID : 777682
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