Seroprevalence and Risk Factors of Crimean-Congo Hemorrhagic Fever in Cattle of Smallholder Farmers in Central Malawi.

Crimean-Congo hemorrhagic fever virus Malawi cattle seroprevalence

Journal

Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317

Informations de publication

Date de publication:
10 Dec 2021
Historique:
received: 14 11 2021
revised: 07 12 2021
accepted: 07 12 2021
entrez: 28 12 2021
pubmed: 29 12 2021
medline: 29 12 2021
Statut: epublish

Résumé

Crimean-Congo hemorrhagic fever virus (CCHFV) is endemic in Africa, Asia, and Eastern Europe where it circulates among animals and ticks causing sporadic outbreaks in humans. Although CCHF is endemic in sub-Saharan Africa, epidemiological information is lacking in many countries, including Malawi. To assess the risk of CCHF in Malawi, we conducted an epidemiological study in cattle reared by smallholder livestock farmers in central Malawi. A cross-sectional study was conducted in April 2020 involving seven districts, four from Kasungu and three from Lilongwe Agriculture Development Divisions. A structured questionnaire was administered to farmers to obtain demographic, animal management, and ecological risk factors data. Sera were collected from randomly selected cattle and screened for CCHF virus (CCHFV) specific antibodies using a commercial ELISA kit. Ticks were collected from cattle and classified morphologically to species level. An overall CCHFV seropositivity rate of 46.9% (

Identifiants

DOI: 10.3390/pathogens10121613 PMID: 34959568 PMC: PMC8709441
pubmed: 34959568
pii: pathogens10121613
doi: 10.3390/pathogens10121613
pmc: PMC8709441
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : World Bank
ID : P151847
Organisme : Japan Agency for Medical Research and Development
ID : JP21jm0110019
Organisme : Japan Program for Infectious Diseases Research and Development
ID : JP21wm0125008

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Auteurs

Marvin Collen Phonera (MC)

Department of Animal Health and Livestock Development, Ministry of Agriculture, Lilongwe 207203, Malawi.
Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Africa Center of Excellence for Infectious Diseases of Humans and Animals, University of Zambia, Lusaka 10101, Zambia.
ORCID: 0000-0002-5733-9844

Martin Chitolongo Simuunza (MC)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Africa Center of Excellence for Infectious Diseases of Humans and Animals, University of Zambia, Lusaka 10101, Zambia.

Henson Kainga (H)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Africa Center of Excellence for Infectious Diseases of Humans and Animals, University of Zambia, Lusaka 10101, Zambia.
Department of Veterinary Medicine, Lilongwe University of Agriculture and Natural Resources, Lilongwe 207203, Malawi.

Joseph Ndebe (J)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.

Mwelwa Chembensofu (M)

Department of Para-Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.

Elisha Chatanga (E)

Department of Veterinary Medicine, Lilongwe University of Agriculture and Natural Resources, Lilongwe 207203, Malawi.
Laboratory of Parasitology, Graduate School of Infectious Diseases, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido 060-8588, Japan.
ORCID: 0000-0001-5448-2605

Setiala Kanyanda (S)

International Training and Education Center for Health, Lilongwe 207203, Malawi.

Katendi Changula (K)

Department of Para-Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
ORCID: 0000-0003-2182-4319

Walter Muleya (W)

Department of Biomedical Sciences, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.

Benjamin Mubemba (B)

Department of Wildlife Sciences, School of Natural Resources, Copperbelt University, Kitwe 50100, Zambia.
Department of Biomedical Sciences, School of Medicine, Copperbelt University, Ndola 50100, Zambia.
ORCID: 0000-0002-5266-3602

Simbarashe Chitanga (S)

Department of Paraclinical Studies, School of Veterinary Medicine, University of Namibia, Windhoek 10005, Namibia.
Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka 10101, Zambia.
School of Life Sciences, College of Agriculture, Engineering and Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
ORCID: 0000-0002-5384-2493

Masahiro Kajihara (M)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.

Hirofumi Sawa (H)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Division of International Research Promotion, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Global Virus Network, Baltimore, ML 21201, USA.
International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
One Health Research Center, Hokkaido University, Sapporo 001-0020, Japan.
ORCID: 0000-0003-2569-2755

Gilson Njunga (G)

Department of Animal Health and Livestock Development, Ministry of Agriculture, Lilongwe 207203, Malawi.

Ayato Takada (A)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
ORCID: 0000-0003-2464-6642

Edgar Simulundu (E)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka 10101, Zambia.
Macha Research Trust, Choma 20100, Zambia.
ORCID: 0000-0001-9423-0816

Classifications MeSH