Medication Discrepancies and Regimen Complexity in Decompensated Cirrhosis: Implications for Medication Safety.

clinical pharmacist medication complexity medication reconciliation medication related problems medication safety

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
23 Nov 2021
Historique:
received: 27 10 2021
revised: 16 11 2021
accepted: 16 11 2021
entrez: 28 12 2021
pubmed: 29 12 2021
medline: 29 12 2021
Statut: epublish

Résumé

Discrepancies between the medicines consumed by patients and those documented in the medical record can affect medication safety. We aimed to characterize medication discrepancies and medication regimen complexity over time in a cohort of outpatients with decompensated cirrhosis, and evaluate the impact of pharmacist-led intervention on discrepancies and patient outcomes. In a randomized-controlled trial (

Identifiants

pubmed: 34959611
pii: ph14121207
doi: 10.3390/ph14121207
pmc: PMC8703811
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : University of Queensland
ID : Research Scholarship
Organisme : Health Innovation, Investment and Research Office
ID : Queensland Advancing Clinical Research Fellowship
Organisme : National Health and Medical Research Council
ID : Career Development Fellowship (no. 1083090)

Références

Ann Pharmacother. 2004 Sep;38(9):1369-76
pubmed: 15266038
J Eval Clin Pract. 2015 Oct;21(5):831-9
pubmed: 26032916
Am J Geriatr Pharmacother. 2006 Mar;4(1):36-41
pubmed: 16730619
J Chronic Dis. 1987;40(5):373-83
pubmed: 3558716
Res Social Adm Pharm. 2018 Apr;14(4):340-346
pubmed: 28412152
J Family Med Prim Care. 2017 Jan-Mar;6(1):78-82
pubmed: 29026754
BMC Gastroenterol. 2016 Sep 13;16:114
pubmed: 27618841
Drug Saf. 2019 Apr;42(4):539-546
pubmed: 30357649
Hepatol Commun. 2019 Mar 18;3(5):620-631
pubmed: 31061951
Clin Ther. 2013 Apr;35(4):385-398.e1
pubmed: 23541707
Ann Pharmacother. 2014 Jun 17;48(9):1129-1137
pubmed: 24939633
Clin Interv Aging. 2017 Apr 12;12:679-686
pubmed: 28442898
Arch Intern Med. 2000 Jul 24;160(14):2129-34
pubmed: 10904455
Arch Intern Med. 2005 Sep 12;165(16):1842-7
pubmed: 16157827
Ann Pharmacother. 2014 Feb;48(2):168-77
pubmed: 24259649
J Am Pharm Assoc (2003). 2012 Jan-Feb;52(1):59-66
pubmed: 22257617
Ann Pharmacother. 2016 Nov;50(11):926-934
pubmed: 27371949
Hepatol Commun. 2020 Oct 10;4(11):1562-1577
pubmed: 33163829
Expert Opin Drug Metab Toxicol. 2020 Jan;16(1):45-57
pubmed: 31810397
J Patient Saf. 2014 Dec;10(4):186-91
pubmed: 25408236
J Am Pharm Assoc (2003). 2017 Jul - Aug;57(4):488-492
pubmed: 28495145
United European Gastroenterol J. 2021 Mar;9(2):193-202
pubmed: 33226300
Hepatology. 2021 Jun;73(6):2429-2440
pubmed: 32911564

Auteurs

Kelly L Hayward (KL)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
Pharmacy Department, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Patricia C Valery (PC)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia.

Preya J Patel (PJ)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Catherine Li (C)

Pharmacy Department, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Leigh U Horsfall (LU)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Penny L Wright (PL)

Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Caroline J Tallis (CJ)

Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Katherine A Stuart (KA)

Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Michael David (M)

School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, Newcastle, NSW 2308, Australia.

Katharine M Irvine (KM)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
Mater Research, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.

Neil Cottrell (N)

Faculty of Health and Behavioral Sciences, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia.

Jennifer H Martin (JH)

School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, Newcastle, NSW 2308, Australia.

Elizabeth E Powell (EE)

Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia.
Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, QLD 4102, Australia.

Classifications MeSH