The Therapeutic Potential of Common Herbal and Nano-Based Herbal Formulations against Ovarian Cancer: New Insight into the Current Evidence.

curcumin herbal medicine nanotechnology quercetin resveratrol

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
17 Dec 2021
Historique:
received: 04 11 2021
revised: 28 11 2021
accepted: 30 11 2021
entrez: 28 12 2021
pubmed: 29 12 2021
medline: 29 12 2021
Statut: epublish

Résumé

Ovarian cancer (OCa) is characterized as one of the common reasons for cancer-associated death in women globally. This gynecological disorder is chiefly named the "silent killer" due to lacking an association between disease manifestations in the early stages and OCa. Because of the disease recurrence and resistance to common therapies, discovering an effective therapeutic way against the disease is a challenge. According to documents, some popular herbal formulations, such as curcumin, quercetin, and resveratrol, can serve as an anti-cancer agent through different mechanisms. However, these herbal products may be accompanied by some pharmacological limitations, such as poor bioavailability, instability, and weak water solubility. On the contrary, using nano-based material, e.g., nanoparticles (NPs), micelles, liposomes, can significantly solve these limitations. Therefore, in the present study, we will summarize the anti-cancer aspects of these herbal and-nano-based herbal formulations with a focus on their mechanisms against OCa.

Identifiants

pubmed: 34959716
pii: ph14121315
doi: 10.3390/ph14121315
pmc: PMC8705681
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Fatemeh Rezaei-Tazangi (F)

Department of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa 7345149573, Iran.

Hossein Roghani-Shahraki (H)

Student Research Committee, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.

Mahdi Khorsand Ghaffari (M)

Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.

Firoozeh Abolhasani Zadeh (F)

Department of Surgery, Faculty of Medicine, Kerman University of Medical Sciences, Kerman 7616913555, Iran.

Aynaz Boostan (A)

Department of Obstetrics & Gynecology, Saveh Chamran Hospital, Saveh 3919676651, Iran.

Reza ArefNezhad (R)

Department of Anatomy, School of Medicine, Shiraz University of Medical Sciences, Shiraz 1433671348, Iran.

Hossein Motedayyen (H)

Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan 8715973474, Iran.

Classifications MeSH