Beneficial Properties of Bromelain.
Ananas
/ enzymology
Anti-Inflammatory Agents
/ chemistry
Anticoagulants
/ chemistry
Blood Coagulation Disorders
/ drug therapy
Bromelains
/ chemistry
Cardiotonic Agents
/ chemistry
Cardiovascular Diseases
/ drug therapy
Fibrinolysis
/ drug effects
Humans
Neoplasms
/ drug therapy
Plant Proteins
/ chemistry
SARS-CoV-2
COVID-19 Drug Treatment
COVID-19 disease
SARS-CoV-2 virus
bromelain
cancer
cardiovascular diseases
coagulation
fibrinolysis
inflammation
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
29 Nov 2021
29 Nov 2021
Historique:
received:
03
11
2021
revised:
26
11
2021
accepted:
27
11
2021
entrez:
28
12
2021
pubmed:
29
12
2021
medline:
5
1
2022
Statut:
epublish
Résumé
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high availability, and relative simplicity of acquisition, it is the object of inexhaustible interest of scientists. This review summarizes scientific reports concerning the possible application of bromelain in treating cardiovascular diseases, blood coagulation and fibrinolysis disorders, infectious diseases, inflammation-associated diseases, and many types of cancer. However, for the proper application of such multi-action activities of bromelain, further exploration of the mechanism of its action is needed. It is supposed that the anti-viral, anti-inflammatory, cardioprotective and anti-coagulatory activity of bromelain may become a complementary therapy for COVID-19 and post-COVID-19 patients. During the irrepressible spread of novel variants of the SARS-CoV-2 virus, such beneficial properties of this biomolecule might help prevent escalation and the progression of the COVID-19 disease.
Identifiants
pubmed: 34959865
pii: nu13124313
doi: 10.3390/nu13124313
pmc: PMC8709142
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Anticoagulants
0
Cardiotonic Agents
0
Plant Proteins
0
Bromelains
9001-00-7
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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