Novel frontiers of agents for bowel cleansing for colonoscopy.


Journal

World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448

Informations de publication

Date de publication:
07 Dec 2021
Historique:
received: 17 03 2021
revised: 23 04 2021
accepted: 24 11 2021
entrez: 29 12 2021
pubmed: 30 12 2021
medline: 31 12 2021
Statut: ppublish

Résumé

The incidence of colorectal cancer (CRC) is characterized by rapid declines in the wake of widespread screening. Colonoscopy is the gold standard for CRC screening, but its accuracy is related to high quality of bowel preparation (BP). In this review, we aimed to summarized the current strategy to increase bowel cleansing before colonoscopy. Newly bowel cleansing agents were developed with the same efficacy of previous agent but requiring less amount of liquid to improve patients' acceptability. The role of the diet before colonoscopy was also changed, as well the contribution of educational intervention and the use of adjunctive drugs to improve patients' tolerance and/or quality of BP. The review also described BP in special situations, as lower gastrointestinal bleeding, elderly people, patients with chronic kidney disease, patients with inflammatory bowel disease, patients with congestive heart failure, inpatient, patient with previous bowel resection, pregnant/lactating patients. The review underlined the quality of BP should be described using a validate scale in colonoscopy report and it explored the available scales. Finally, the review explored the possible contribution of bowel cleansing in post-colonoscopy syndrome that can be related by a transient alteration of gut microbiota. Moreover, the study underlined several points needed to further investigations.

Identifiants

pubmed: 34963739
doi: 10.3748/wjg.v27.i45.7748
pmc: PMC8661374
doi:

Substances chimiques

Cathartics 0
Polyethylene Glycols 3WJQ0SDW1A

Types de publication

Editorial Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

7748-7770

Informations de copyright

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: No conflict-of-interest.

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Auteurs

Milena Di Leo (M)

Unit of Digestive Endoscopy, San Paolo Hospital, Milan 20090, Italy.

Andrea Iannone (A)

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.

Monica Arena (M)

Unit of Digestive Endoscopy, San Paolo Hospital, Milan 20090, Italy.

Giuseppe Losurdo (G)

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.

Maria Angela Palamara (MA)

Unit of Digestive Endoscopy, San Paolo Hospital, Milan 20090, Italy.

Giuseppe Iabichino (G)

Unit of Digestive Endoscopy, San Paolo Hospital, Milan 20090, Italy.

Pierluigi Consolo (P)

Unit of Digestive Endoscopy, University of Messina, Hospital "G. Martino", Messina 98121, Italy.

Maria Rendina (M)

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.

Carmelo Luigiano (C)

Unit of Digestive Endoscopy, San Paolo Hospital, Milan 20090, Italy.

Alfredo Di Leo (A)

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy. alfredo.dileo@uniba.it.

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