Subgingival pathogens in chronic periodontitis patients affected by type 2 diabetes mellitus: a retrospective case-control study.

Microbiology Periodontitis Tannerella forsythia Type 2 diabetes

Journal

Journal of periodontal & implant science
ISSN: 2093-2278
Titre abrégé: J Periodontal Implant Sci
Pays: Korea (South)
ID NLM: 101526931

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 28 12 2020
revised: 20 03 2021
accepted: 26 04 2021
entrez: 29 12 2021
pubmed: 30 12 2021
medline: 30 12 2021
Statut: ppublish

Résumé

The aim of this study was to compare the prevalence and bacterial load of 6 main periodontal pathogens between pairs of periodontal patients with and without type 2 diabetes mellitus. Twenty patients affected by chronic periodontitis and type 2 diabetes were retrospectively selected and matched to 20 patients without diabetes on the basis of the degree and severity of periodontal disease. Microbiological data of subgingival biofilms were analysed and compared for the examined pathogens: The pairs were balanced in terms of demographic and clinical parameters, except for bleeding on probing and suppuration. In the microbiological test sites (4 for each patient), the mean probing pocket depth was 6.34±1.63 mm in patients with diabetes and 6.41±1.78 mm in patients without diabetes. No significant difference between pairs in the prevalence of This retrospective matched study supports the hypothesis that microbiological differences exist among periodontal patients with and without diabetes mellitus. ClinicalTrials.gov Identifier: NCT03786133.

Identifiants

pubmed: 34965620
pii: 51.409
doi: 10.5051/jpis.2100180009
pmc: PMC8718332
doi:

Banques de données

ClinicalTrials.gov
['NCT03786133']

Types de publication

Journal Article

Langues

eng

Pagination

409-421

Informations de copyright

Copyright © 2021. Korean Academy of Periodontology.

Déclaration de conflit d'intérêts

No potential conflict of interest relevant to this article was reported.

Références

J Clin Periodontol. 2013 Apr;40 Suppl 14:S113-34
pubmed: 23627323
J Periodontal Res. 2018 Jun;53(3):315-323
pubmed: 29110296
J Clin Periodontol. 2006 Dec;33(12):855-62
pubmed: 17092237
J Periodontal Res. 2001 Feb;36(1):18-24
pubmed: 11246700
J Appl Oral Sci. 2017 Jan-Feb;25(1):82-89
pubmed: 28198980
J Periodontal Res. 2013 Feb;48(1):30-6
pubmed: 22762355
Diabetes Educ. 1992 Jul-Aug;18(4):310-5
pubmed: 1628532
Ann Periodontol. 2001 Dec;6(1):99-112
pubmed: 11887478
J Clin Periodontol. 2018 Aug;45(8):932-940
pubmed: 29742293
New Microbiol. 2014 Oct;37(4):517-24
pubmed: 25387289
Anaerobe. 2004 Feb;10(1):27-32
pubmed: 16701497
Clin Oral Investig. 2018 Nov;22(8):2743-2762
pubmed: 30306333
Ann Periodontol. 1999 Dec;4(1):1-6
pubmed: 10863370
J Clin Periodontol. 2016 Nov;43(11):889-900
pubmed: 27440507
J Periodontol. 2013 Aug;84(8):1058-66
pubmed: 23030242
J Clin Periodontol. 2006 Nov;33(11):784-90
pubmed: 16911568
Oral Health Prev Dent. 2016;14(4):329-37
pubmed: 26870849
J Dent Res. 2014 Nov;93(11):1045-53
pubmed: 25261053
Infect Immun. 1989 Jun;57(6):1757-9
pubmed: 2722237
J Clin Periodontol. 1998 Feb;25(2):134-44
pubmed: 9495612
J Diabetes Complications. 2006 Jan-Feb;20(1):59-68
pubmed: 16389170
Oral Microbiol Immunol. 2008 Aug;23(4):348-51
pubmed: 18582336
J Periodontal Res. 1975 Jul;10(3):171-5
pubmed: 126316
PLoS One. 2013 Apr 22;8(4):e61516
pubmed: 23613868
J Periodontol. 2008 Apr;79(4):637-46
pubmed: 18380556
Diabetologia. 2012 Jan;55(1):21-31
pubmed: 22057194
J Am Dent Assoc. 2006 Oct;137 Suppl:26S-31S
pubmed: 17012733
Lancet. 2005 Nov 19;366(9499):1809-20
pubmed: 16298220
Arch Oral Biol. 2011 Oct;56(10):1098-105
pubmed: 21529777
J Periodontal Res. 2012 Aug;47(4):470-8
pubmed: 22220967
J Clin Periodontol. 2018 Jun;45 Suppl 20:S149-S161
pubmed: 29926495
Microbiol Res. 2005;160(3):257-63
pubmed: 16035237
J Periodontol. 2015 Jul;86(7):835-8
pubmed: 26125117
J Clin Periodontol. 2000 Jun;27(6):387-94
pubmed: 10883867
J Clin Periodontol. 2014 Mar;41(3):232-41
pubmed: 24304011
J Clin Periodontol. 2018 Feb;45(2):150-166
pubmed: 29280184
J Bacteriol. 2016 Oct 21;198(22):3119-3125
pubmed: 27601356
J Clin Periodontol. 2007 Jan;34(1):25-30
pubmed: 17116161
Curr Opin Dent. 1992 Mar;2:5-11
pubmed: 1520938

Auteurs

Marco Montevecchi (M)

Division of Periodontology and Implantology, Department of Biomedical and Neuromotor Sciences, School of Dentistry, Alma Mater Studiorum - University of Bologna, Bologna, Italy. m.montevecchi@unibo.it.

Leoluca Valeriani (L)

Division of Periodontology and Implantology, Department of Biomedical and Neuromotor Sciences, School of Dentistry, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Maria Rosaria Gatto (MR)

Department of Biomedical and Neuromotor Sciences, School of Dentistry, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Giovanni D'Alessandro (G)

Dentistry Service for Patients with Special Needs, Department of Biomedical and Neuromotor Sciences, School of Dentistry, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Gabriela Piana (G)

Dentistry Service for Patients with Special Needs, Department of Biomedical and Neuromotor Sciences, School of Dentistry, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Classifications MeSH