Ketone Bodies Impact on Hypoxic CO
CO2
beta-hydroxybutyrate
cognition
exercise
hypoxia
ketone bodies
metabolism
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2021
2021
Historique:
received:
21
09
2021
accepted:
15
11
2021
entrez:
30
12
2021
pubmed:
31
12
2021
medline:
31
12
2021
Statut:
epublish
Résumé
Exogenous ketone esters have demonstrated the capacity to increase oxygen availability during acute hypoxic exposure leading to the potential application of their use to mitigate performance declines at high altitudes. Voluntary hypoventilation (VH) with exercise reliably reduces oxygen availability and increases carbon dioxide retention without alterations to ambient pressure or gas content. Utilizing a double-blind randomized crossover design, fifteen recreational male distance runners performed submaximal exercise (4 × 5 min; 70% VO
Identifiants
pubmed: 34966291
doi: 10.3389/fphys.2021.780755
pmc: PMC8711099
doi:
Types de publication
Journal Article
Langues
eng
Pagination
780755Informations de copyright
Copyright © 2021 Prins, Buxton, McClure, D’Agostino, Ault, Welton, Jones, Atwell, Slack, Slack, Williams, Blanchflower, Kannel, Faulkner, Szmaciasz, Croll, Stanforth, Harris, Gwaltney and Koutnik.
Déclaration de conflit d'intérêts
AK is a consultant for Simply Good Foods Inc. DD’A is co-owner of Ketone Technologies LLC, providing scientific consulting and public speaking on ketogenic therapies, and receives royalties in accordance with University of South Florida policy patent policy. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Eur J Sport Sci. 2017 Sep;17(8):1037-1043
pubmed: 28557670
Int J Sport Nutr Exerc Metab. 2019 Nov 21;:1-8
pubmed: 31751935
Med Sci Sports Exerc. 2019 Dec;51(12):2506-2515
pubmed: 31730565
J Physiol Sci. 2018 Nov;68(6):847-853
pubmed: 29536370
J Physiol. 2017 May 1;595(9):2857-2871
pubmed: 27861911
J Sport Health Sci. 2020 Dec;9(6):562-577
pubmed: 32325144
Int J Sport Nutr Exerc Metab. 2009 Oct;19(5):485-503
pubmed: 19910651
Front Physiol. 2019 Mar 29;10:290
pubmed: 30984015
JAMA. 2019 Sep 24;322(12):1178-1187
pubmed: 31550032
Arch Clin Neuropsychol. 2007 Feb;22 Suppl 1:S101-14
pubmed: 17118625
Neurosci Biobehav Rev. 2017 Mar;74(Pt A):225-232
pubmed: 28111267
Can J Sport Sci. 1991 Mar;16(1):23-9
pubmed: 1645211
Scand J Med Sci Sports. 2020 Mar;30(3):384-398
pubmed: 31605635
Int J Sports Med. 2011 Jun;32(6):438-45
pubmed: 21563023
Eur Respir J. 1999 Jul;14(1):214-7
pubmed: 10489854
Aerosp Med Hum Perform. 2021 Jul 1;92(7):556-562
pubmed: 34503629
Am J Cardiol. 1997 Aug 4;80(3A):50A-64A
pubmed: 9293956
Eur J Appl Physiol. 2019 Sep;119(9):1959-1970
pubmed: 31286240
Nutr Metab (Lond). 2020 Sep 29;17:81
pubmed: 33005207
Respir Physiol Neurobiol. 2008 Feb 1;160(2):123-30
pubmed: 18160351
Cell Metab. 2016 Aug 9;24(2):256-68
pubmed: 27475046
Crit Care. 2011 Apr 06;15(2):219
pubmed: 21489321
Brain Res Rev. 2009 Mar;59(2):293-315
pubmed: 18845187
Int J Sports Physiol Perform. 2018 Jul 1;13(6):783-788
pubmed: 29140137
Expert Rev Respir Med. 2018 Feb;12(2):113-123
pubmed: 29241369
Brain Res. 2012 May 9;1453:87-101
pubmed: 22480735
J Appl Physiol (1985). 2021 Jun 1;130(6):1936-1954
pubmed: 33661724
Front Physiol. 2017 Oct 30;8:848
pubmed: 29163194
Med Sci Sports Exerc. 2018 Nov;50(11):2330-2338
pubmed: 29944604
Med Sci Sports Exerc. 2004 Jan;36(1):102-8
pubmed: 14707775
Prostaglandins Leukot Essent Fatty Acids. 2004 Mar;70(3):309-19
pubmed: 14769489
Neurobiol Aging. 2004 Mar;25(3):311-4
pubmed: 15123336
J Appl Physiol Respir Environ Exerc Physiol. 1983 Aug;55(2):628-34
pubmed: 6618956
FASEB J. 1995 May;9(8):651-8
pubmed: 7768357
Alzheimers Dement. 2021 Mar;17(3):543-552
pubmed: 33103819
Front Physiol. 2017 Oct 23;8:806
pubmed: 29109686
Am J Physiol. 1982 Jul;243(1):R7-17
pubmed: 7091397
Eur J Appl Physiol. 2010 Sep;110(2):367-77
pubmed: 20503056
Am J Physiol. 1996 May;270(5 Pt 1):E746-51
pubmed: 8967461
Curr Sports Med Rep. 2020 Jul;19(7):251-259
pubmed: 32692060
Appl Physiol Nutr Metab. 2017 Oct;42(10):1031-1035
pubmed: 28750585
Eur J Appl Physiol. 2017 Dec;117(12):2433-2443
pubmed: 29032393
Am J Physiol. 1981 Mar;240(3):E253-62
pubmed: 7011051
J Strength Cond Res. 2001 Feb;15(1):109-15
pubmed: 11708692
Med Sci Sports Exerc. 2021 Mar 1;53(3):505-516
pubmed: 32868580
Eur J Sport Sci. 2018 May;18(4):504-512
pubmed: 29400616
Respir Med. 2007 Mar;101(3):399-410
pubmed: 16914301
Eur J Sport Sci. 2018 Apr;18(3):376-386
pubmed: 29338584
J Alzheimers Dis. 2018;64(2):551-561
pubmed: 29914035
Med Sci Sports Exerc. 2021 Feb 1;53(2):431-441
pubmed: 32735112