How Does COVID-19 Pandemic Impact on Incidence of

COVID-19 Clostridioides difficile infection NSAIDs antibiotic therapy coronavirus disease 2019 elderly gut microbiota

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2021
Historique:
received: 13 09 2021
accepted: 22 11 2021
entrez: 30 12 2021
pubmed: 31 12 2021
medline: 31 12 2021
Statut: epublish

Résumé

Coronavirus disease 2019 (COVID-19) has rapidly spread all over the world with a very high rate of mortality. Different symptoms developed by COVID-19 infection and its impacts on various organs of the human body have highlighted the importance of both coinfections and superinfections with other pathogens. The gastrointestinal (GI) tract is vulnerable to infection with COVID-19 and can be exploited as an alternative transmission route and target for virus entry and pathogenesis. The GI manifestations of COVID-19 disease are associated with severe disease outcomes and death in all age groups, in particular, elderly patients. Empiric antibiotic treatments for microbial infections in hospitalized patients with COVID-19 in addition to experimental antiviral and immunomodulatory drugs may increase the risk of antibiotic-associated diarrhea (AAD) and

Identifiants

pubmed: 34966759
doi: 10.3389/fmed.2021.775063
pmc: PMC8710593
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

775063

Informations de copyright

Copyright © 2021 Azimirad, Noori, Raeisi, Yadegar, Shahrokh, Asadzadeh Aghdaei, Bentivegna, Martelletti, Petrosillo and Zali.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Masoumeh Azimirad (M)

Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Maryam Noori (M)

Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Hamideh Raeisi (H)

Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abbas Yadegar (A)

Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Shabnam Shahrokh (S)

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Hamid Asadzadeh Aghdaei (H)

Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Enrico Bentivegna (E)

Internal Medicine and Emergency Medicine, St'Andrea Hospital, Sapienza University, Rome, Italy.

Paolo Martelletti (P)

Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.

Nicola Petrosillo (N)

Infectious Diseases Service, University Hospital Campus Bio-Medico, Rome, Italy.

Mohammad Reza Zali (MR)

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Classifications MeSH