Postoperative Quality of Life After Full-sternotomy and Ministernotomy Aortic Valve Replacement.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
05 2023
Historique:
received: 25 05 2021
revised: 16 10 2021
accepted: 29 11 2021
medline: 25 4 2023
pubmed: 1 1 2022
entrez: 31 12 2021
Statut: ppublish

Résumé

Few longitudinal data exist comparing quality of life (QoL) after full sternotomy (fs) aortic valve replacement (AVR) (fsAVR) with ministernotomy AVR (msAVR). A total of 1844 consecutive patients undergoing AVR who were prospectively enrolled in a European multicenter registry were dichotomized according to surgical access. Nonparsimonious propensity score matching selected 187 pairs of patients who underwent fsAVR or msAVR with comparable baseline characteristics. Hospital outcome was compared in the 2 groups. QoL was assessed with the Short Form-36, further detailed in its Physical Component Summary (PCS) score and the Mental Component Summary (MCS) score. QoL was investigated at hospital admission, at discharge, and at 1 month, 6 months, and 1 year thereafter. There were 1654 patients undergoing fsAVR and 190 undergoing msAVR in the entire population. The fsAVR group showed a worse preoperative risk profile, a longer intensive care unit length of stay (59.7 hours vs 38.8 hours; p = .002), and a higher rate of life-threatening or disabling bleeding (4.1% vs 0%; P = .011); the msAVR group had a higher rate of early reintervention for failed index intervention (2.1% vs 0.5%; P = .001). QoL investigations showed better PCS and MCS at 1 month after fsAVR, but no temporal trend differences (PCS group-time P = .202; MCS group-time P = .141). Propensity-matched pairs showed comparable baseline characteristics and hospital outcomes (P = not significant for all end points) and comparable improvements of PCS and MCS over time, but no between-group differences over time (PCS group time P = .834; MCS group time P = .737). Patients with similar baseline profiles report comparable hospital outcomes and comparable improvements of physical and mental health, up to 1 year after surgery, with both fsAVR and msAVR. As for QoL, ministernotomy does not seem to offer any advantage compared with the traditional approach.

Sections du résumé

BACKGROUND
Few longitudinal data exist comparing quality of life (QoL) after full sternotomy (fs) aortic valve replacement (AVR) (fsAVR) with ministernotomy AVR (msAVR).
METHODS
A total of 1844 consecutive patients undergoing AVR who were prospectively enrolled in a European multicenter registry were dichotomized according to surgical access. Nonparsimonious propensity score matching selected 187 pairs of patients who underwent fsAVR or msAVR with comparable baseline characteristics. Hospital outcome was compared in the 2 groups. QoL was assessed with the Short Form-36, further detailed in its Physical Component Summary (PCS) score and the Mental Component Summary (MCS) score. QoL was investigated at hospital admission, at discharge, and at 1 month, 6 months, and 1 year thereafter.
RESULTS
There were 1654 patients undergoing fsAVR and 190 undergoing msAVR in the entire population. The fsAVR group showed a worse preoperative risk profile, a longer intensive care unit length of stay (59.7 hours vs 38.8 hours; p = .002), and a higher rate of life-threatening or disabling bleeding (4.1% vs 0%; P = .011); the msAVR group had a higher rate of early reintervention for failed index intervention (2.1% vs 0.5%; P = .001). QoL investigations showed better PCS and MCS at 1 month after fsAVR, but no temporal trend differences (PCS group-time P = .202; MCS group-time P = .141). Propensity-matched pairs showed comparable baseline characteristics and hospital outcomes (P = not significant for all end points) and comparable improvements of PCS and MCS over time, but no between-group differences over time (PCS group time P = .834; MCS group time P = .737).
CONCLUSIONS
Patients with similar baseline profiles report comparable hospital outcomes and comparable improvements of physical and mental health, up to 1 year after surgery, with both fsAVR and msAVR. As for QoL, ministernotomy does not seem to offer any advantage compared with the traditional approach.

Identifiants

pubmed: 34971595
pii: S0003-4975(21)02143-3
doi: 10.1016/j.athoracsur.2021.11.055
pii:
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1189-1196

Informations de copyright

Copyright © 2023 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Andrea Perrotti (A)

Department of Thoracic and Cardiovascular Surgery, University of Franche-Comte, Besancon, France.

Alessandra Francica (A)

Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy.

Francesco Monaco (F)

Department of Thoracic and Cardiovascular Surgery, University of Franche-Comte, Besancon, France.

Edward Quintana (E)

Division of Cardiac Surgery, Hospital Clinic, University of Barcelona Medical School, Barcelona, Spain.

Sandro Sponga (S)

Division of Cardiac Surgery, Udine University Hospital, Udine, Italy.

Zein El-Dean (Z)

Department of Cardiac Surgery, Glenfield Hospital, University Hospitals of Leicester, Leicester, United Kingdom.

Stefano Salizzoni (S)

Department of Cardiac Surgery, Città della Salute e della Scienza, University of Turin Medical School, Turin, Italy.

Tommaso Loizzo (T)

Cardiac Surgery Unit, Department of Emergency and Organ Transplants, Bari, Italy.

Antonio Salsano (A)

Division of Cardiac Surgery, IRCCS San Martino Polyclinic Hospital, University of Genova, Genova, Italy.

Alessandro Di Cesare (A)

Cardiovascular and Thoracic Surgery Unit, Robert Debre University Hospital, Reims, France; University of Reims Champagne-Ardennes, Reims, France.

Filippo Benassi (F)

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Manuel Castella (M)

Division of Cardiac Surgery, Hospital Clinic, University of Barcelona Medical School, Barcelona, Spain.

Mauro Rinaldi (M)

Department of Cardiac Surgery, Città della Salute e della Scienza, University of Turin Medical School, Turin, Italy.

Sidney Chocron (S)

Department of Thoracic and Cardiovascular Surgery, University of Franche-Comte, Besancon, France.

Igor Vendramin (I)

Division of Cardiac Surgery, Udine University Hospital, Udine, Italy.

Giuseppe Faggian (G)

Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy.

Francesco Santini (F)

Division of Cardiac Surgery, IRCCS San Martino Polyclinic Hospital, University of Genova, Genova, Italy.

Francesco Nicolini (F)

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Aldo Domenico Milano (AD)

Cardiac Surgery Unit, Department of Emergency and Organ Transplants, Bari, Italy.

Vito Giovanni Ruggieri (VG)

Cardiovascular and Thoracic Surgery Unit, Robert Debre University Hospital, Reims, France; University of Reims Champagne-Ardennes, Reims, France.

Francesco Onorati (F)

Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy. Electronic address: francesco.onorati@univr.it.

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