Platelet-Rich Fibrin, Preparation and Use in Dermatology.
A-PRF
C-PRF
I-PRF
RCF
RPM
centrifuge
platelet-rich fibrin guidelines
platelet-rich plasma
preparation
recommendations
regenerative medicine
standardization
Journal
Indian dermatology online journal
ISSN: 2229-5178
Titre abrégé: Indian Dermatol Online J
Pays: India
ID NLM: 101586880
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
06
05
2021
revised:
07
06
2021
accepted:
08
06
2021
entrez:
3
1
2022
pubmed:
4
1
2022
medline:
4
1
2022
Statut:
epublish
Résumé
The goal of these recommendations is to provide a framework to practitioners for implementing useful, evidence-based recommendations for the preparation of platelet-rich fibrin (PRF) and its use in various dermatological indications. The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) assigned the task of preparing these recommendations to its taskforce on platelet-rich plasma. A comprehensive literature search was done in the English language on the PRF across multiple databases. The grade of evidence and strength of recommendation was evaluated on the GRADE framework (Grading of Recommendation, Assessment, Development and Evaluation). A draft of clinical recommendations was developed on the best available evidence which was also scrutinized and critically evaluated by the IADVL Academy of Dermatology. Based on the inputs received, this final consensus statement was prepared. A total of 40 articles (meta-analyses, prospective and retrospective studies, reviews [including chapters in books] and case series) were critically evaluated and the evidence thus gathered was used in the preparation of these recommendations. This expert group recommends use of A-PRF+ protocol, that is (200 g for 8 min) for preparation of solid PRF and C-PRF protocol (700 g for 8 min) for liquid PRF. Swing out bucket model of centrifuge or the horizontal centrifuge is recommended for preparation of both PRF, and liquid PRF. Centrifugation must begin within 90-120 s of drawing of blood. PRF can be used in various indications for skin rejuvenation and nonhealing ulcers as either monotherapy or in combination with other therapies.
Identifiants
pubmed: 34976881
doi: 10.4103/idoj.idoj_282_21
pii: IDOJ-12-55
pmc: PMC8664174
doi:
Types de publication
Journal Article
Langues
eng
Pagination
S55-S65Informations de copyright
Copyright: © 2021 Indian Dermatology Online Journal.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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