Adult Intestinal Toxemia Botulism in a Patient With Crohn's Disease.
Journal
ACG case reports journal
ISSN: 2326-3253
Titre abrégé: ACG Case Rep J
Pays: United States
ID NLM: 101638398
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
21
01
2021
accepted:
27
07
2021
entrez:
3
1
2022
pubmed:
4
1
2022
medline:
4
1
2022
Statut:
epublish
Résumé
Adult intestinal toxemia botulism (ITB) is a rare illness that can be fatal if not recognized. ITB can occur when botulinum neurotoxin-producing clostridia colonize the intestine. Underlying intestinal abnormalities associated with dysbiosis are likely a prerequisite for colonization. Dysbiosis seems necessary for spore germination and neurotoxin production. Botulism neurotoxins are the most lethal poisons known and are classified into 7 serotypes: A through G. The clinical presentation consists of cranial nerve abnormalities and descending flaccid paralysis. Prompt recognition and treatment with botulism antitoxin and supportive measures is often successful, but delayed recognition can be fatal. In this study, we present a case of a 40-year-old woman with Crohn's disease who developed ITB. This is the first case in literature to report adult intestinal botulism from
Identifiants
pubmed: 34977262
doi: 10.14309/crj.0000000000000718
pii: ACGCR-21-0093
pmc: PMC8716092
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e00718Informations de copyright
© 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.
Références
N Engl J Med. 1986 Jul 24;315(4):239-41
pubmed: 3523248
N Engl J Med. 2006 Feb 2;354(5):462-71
pubmed: 16452558
J Infect Dis. 1997 Mar;175(3):633-7
pubmed: 9041335
Toxins (Basel). 2020 Jan 24;12(2):
pubmed: 31991691
Clin Infect Dis. 2005 Oct 15;41(8):1167-73
pubmed: 16163636
Neurology. 2005 Dec 13;65(11):1694-700
pubmed: 16344510
Rev Inst Med Trop Sao Paulo. 2019 Sep 12;61:e49
pubmed: 31531627
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S99-S102
pubmed: 29293935
Clin Infect Dis. 2017 Dec 27;66(suppl_1):S43-S56
pubmed: 29293927
J Clin Microbiol. 1991 Nov;29(11):2618-20
pubmed: 1774272
Mayo Clin Proc Innov Qual Outcomes. 2018 Aug 03;2(3):291-296
pubmed: 30225463
Anaerobe. 2014 Oct 18;30:178-180
pubmed: 25463969
Ann Neurol. 1986 Nov;20(5):641-3
pubmed: 3789680
Emerg Infect Dis. 2012 Jan;18(1):1-6
pubmed: 22257757