Design, synthesis and evaluation of tryptophan analogues as tool compounds to study IDO1 activity.


Journal

RSC chemical biology
ISSN: 2633-0679
Titre abrégé: RSC Chem Biol
Pays: England
ID NLM: 101768727

Informations de publication

Date de publication:
02 Dec 2021
Historique:
received: 17 11 2020
accepted: 20 08 2021
entrez: 3 1 2022
pubmed: 4 1 2022
medline: 4 1 2022
Statut: epublish

Résumé

The metabolism of l-tryptophan to

Identifiants

pubmed: 34977580
doi: 10.1039/d0cb00209g
pii: d0cb00209g
pmc: PMC8637876
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1651-1660

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

NJC was a PhD student sponsored by Celentyx Ltd. TT, OQ, CAB are employees of Celentyx Ltd with share options in the company. JG and NMB are Directors of Celentyx Ltd with shareholdings in the company. There are no other conflicts to declare.

Références

Front Immunol. 2018 Jan 31;9:151
pubmed: 29445380
Gene. 2007 Jul 1;396(1):203-13
pubmed: 17499941
J Biol Chem. 1957 Dec;229(2):889-96
pubmed: 13502350
Sci Rep. 2016 Oct 20;6:35169
pubmed: 27762317
J Am Chem Soc. 2009 Sep 16;131(36):12866-7
pubmed: 19737010
Biochemistry. 2011 Apr 12;50(14):2717-24
pubmed: 21361337
Front Immunol. 2014 Aug 11;5:384
pubmed: 25157255
Biochemistry. 2010 Dec 28;49(51):10831-41
pubmed: 21050007
J Bacteriol. 1951 Dec;62(6):691-709
pubmed: 14907621
J Am Chem Soc. 2009 Apr 1;131(12):4186-7
pubmed: 19275153
J Am Chem Soc. 2008 Sep 17;130(37):12299-309
pubmed: 18712870
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3998-4000
pubmed: 279015
Acta Vitaminol Enzymol. 1975;29(1-6):17-20
pubmed: 1244087
J Biomol Screen. 2001 Dec;6(6):429-40
pubmed: 11788061
J Med Chem. 2020 Apr 9;63(7):3552-3562
pubmed: 32073266
Nat Commun. 2017 Nov 22;8(1):1693
pubmed: 29167421
J Biol Chem. 1967 Nov 25;242(22):5260-6
pubmed: 6065097
J Am Chem Soc. 2010 Sep 1;132(34):11993-2005
pubmed: 20698527
Chem Rev. 1996 Nov 7;96(7):2841-2888
pubmed: 11848843
Proc Natl Acad Sci U S A. 1979 Aug;76(8):4084-6
pubmed: 291064
Adv Enzymol Relat Areas Mol Biol. 1969;32:55-96
pubmed: 4978050
J Am Chem Soc. 2010 Apr 21;132(15):5494-500
pubmed: 20353179
Arch Biochem Biophys. 1991 Dec;291(2):326-33
pubmed: 1952947
Bioorg Med Chem Lett. 2011 May 1;21(9):2697-701
pubmed: 21194936
J Am Chem Soc. 2003 Sep 10;125(36):10926-40
pubmed: 12952474
Immunology. 2002 Dec;107(4):452-60
pubmed: 12460190
J Immunother Cancer. 2018 Jun 20;6(1):61
pubmed: 29921320
Tetrahedron. 1967 Jun;23(6):2855-61
pubmed: 6047529
J Exp Med. 2002 Aug 19;196(4):459-68
pubmed: 12186838
Org Lett. 2016 Mar 18;18(6):1470-3
pubmed: 26958741
J Biol Chem. 2002 May 3;277(18):15788-94
pubmed: 11867636
J Am Chem Soc. 2011 Oct 12;133(40):16251-7
pubmed: 21892828
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17371-6
pubmed: 19805032
J Org Chem. 2006 Apr 28;71(9):3527-32
pubmed: 16626136
Cancer Res. 2012 Nov 1;72(21):5435-40
pubmed: 23090118
Oncotarget. 2014 Sep 30;5(18):8136-46
pubmed: 25327557
Eur J Cancer. 2017 May;76:167-182
pubmed: 28324751
FEBS J. 2012 Dec;279(24):4501-9
pubmed: 23083473
J Med Chem. 2015 Dec 24;58(24):9421-37
pubmed: 25970480
Cancer Res. 2007 Aug 1;67(15):7082-7
pubmed: 17671174
J Exp Med. 1999 May 3;189(9):1363-72
pubmed: 10224276
Oncotarget. 2016 Jun 21;7(25):37762-37772
pubmed: 27192116
Biochem Soc Trans. 2008 Dec;36(Pt 6):1120-3
pubmed: 19021508
Expert Opin Ther Pat. 2018 Apr;28(4):317-330
pubmed: 29473428
Cancer Res. 2017 Dec 15;77(24):6795-6811
pubmed: 29247038
J Biol Chem. 1974 Feb 25;249(4):1311-3
pubmed: 4814344
J Biol Inorg Chem. 2017 Apr;22(2-3):175-183
pubmed: 27909919
Biochemistry. 2008 Oct 7;47(40):10677-84
pubmed: 18783250
J Mol Evol. 2007 Dec;65(6):705-14
pubmed: 18026683
FEBS J. 2015 Aug;282(16):3190-8
pubmed: 25755053
Nat Med. 2003 Oct;9(10):1269-74
pubmed: 14502282

Auteurs

Nicholas J Cundy (NJ)

School of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK r.s.grainger@bham.ac.uk.

Roseanna K Hare (RK)

Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK.

Tina Tang (T)

Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.

Andrew G Leach (AG)

Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK sam.butterworth@manchester.ac.uk.

Thomas A Jowitt (TA)

Wellcome Trust Centre for Cell Matrix Research, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK.

Omar Qureshi (O)

Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.

John Gordon (J)

Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.

Nicholas M Barnes (NM)

Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.
Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham Edgbaston Birmingham B15 2TT UK.

Catherine A Brady (CA)

Celentyx Ltd, Birmingham Research Park 97 Vincent Drive Birmingham B15 2SQ UK.
Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham Edgbaston Birmingham B15 2TT UK.

Emma L Raven (EL)

School of Chemistry, University of Bristol Cantock's Close Bristol BS8 1TS UK.

Richard S Grainger (RS)

School of Chemistry, University of Birmingham Edgbaston Birmingham B15 2TT UK r.s.grainger@bham.ac.uk.

Sam Butterworth (S)

Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester Manchester M13 9PL UK sam.butterworth@manchester.ac.uk.

Classifications MeSH