Revised D-A-CH reference values for the intake of biotin.


Journal

European journal of nutrition
ISSN: 1436-6215
Titre abrégé: Eur J Nutr
Pays: Germany
ID NLM: 100888704

Informations de publication

Date de publication:
Jun 2022
Historique:
received: 10 03 2021
accepted: 25 11 2021
pubmed: 4 1 2022
medline: 18 5 2022
entrez: 3 1 2022
Statut: ppublish

Résumé

The reference values for biotin intake for Germany, Austria and Switzerland lead back to a report in 2000. Following a timely update process, they were revised in 2020. For infants aged 0 to < 4 months, adequate biotin supply via human milk was assumed and in consequence the reference value reflects the amount of biotin delivered by human milk. For infants aged 4 to < 12 months, biotin intake was extrapolated from the reference value for younger infants. Due to missing data on average requirement, the reference values for biotin intake for children, adolescents and adults were derived based on observed intake levels. The reference value for lactating women considered in addition biotin losses via human milk. The reference value for biotin intake for infants aged 0 to < 4 months was set at 4 µg/day and for infants aged 4 to < 12 months at 6 µg/day. In children and adolescents, the reference values for biotin intake ranged from 20 µg/day in children 1 to < 4 years to 40 µg/day in youths 15 to < 19 years. For adults including pregnant women, 40 µg/day was derived as reference value for biotin intake. For lactating women, this value was set at 45 µg/day. As deficiency symptoms of biotin do not occur with a usual mixed diet and the average requirement cannot be determined, reference values for an adequate biotin intake for populations from Germany, Austria and Switzerland were derived from biotin intake levels assessed in population-based nutrition surveys.

Identifiants

pubmed: 34977958
doi: 10.1007/s00394-021-02756-0
pii: 10.1007/s00394-021-02756-0
pmc: PMC9106636
doi:

Substances chimiques

Biotin 6SO6U10H04

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1779-1787

Subventions

Organisme : German Nutrition Society
ID : Dr. Alexandra Jungert received an honorarium from the German Nutrition Society (DGE) for developing the first draft of the dietary reference values for biotin intake.

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2021. The Author(s).

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Auteurs

Alexandra Jungert (A)

Interdisciplinary Research Center for Biosystems, Land Use and Nutrition (IFZ), Biometry and Population Genetics, Justus Liebig University, Heinrich-Buff-Ring 26, 35392, Giessen, Germany.

Sabine Ellinger (S)

Department of Nutrition and Food Sciences, Human Nutrition, Rheinische Friedrich-Wilhelms-University Bonn, Meckenheimer Allee 166a, 53115, Bonn, Germany.

Bernhard Watzl (B)

Department of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, Haid-und-Neu-Str. 9, 76131, Karlsruhe, Germany.

Margrit Richter (M)

Department of Science, German Nutrition Society, Godesberger Allee 136, 53175, Bonn, Germany. richter@dge.de.

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