Spinal malformation - A biochemical analysis using congenital kyphosis rats.
DNA microarrays
kyphosis model rats
microRNA array
spinal malformation
Journal
Journal of cellular biochemistry
ISSN: 1097-4644
Titre abrégé: J Cell Biochem
Pays: United States
ID NLM: 8205768
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
revised:
25
11
2021
received:
21
07
2021
accepted:
17
12
2021
pubmed:
4
1
2022
medline:
14
4
2022
entrez:
3
1
2022
Statut:
ppublish
Résumé
Spinal kyphosis involves the vertebrae curving excessively backward, beyond their physiological curvature. Although the normal structure of the spinal vertebrae is extremely important for maintaining posture, the normal function of the thoracic and abdominal organs, and cosmetics, our knowledge concerning the pathogenesis of this disease is lacking. Furthermore, the responsible gene has not yet been identified. In this short review, we summarize the current state of kyphosis research and introduce the molecular and cellular mechanisms associated with the pathogenesis of this disease, based on findings obtained using rats that develop kyphosis.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
501-505Informations de copyright
© 2021 Wiley Periodicals LLC.
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