Anterior cervical corpectomy and fusion with stand-alone cages in patients with multilevel degenerative cervical spine disease is safe.


Journal

BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565

Informations de publication

Date de publication:
03 Jan 2022
Historique:
received: 15 05 2021
accepted: 26 10 2021
entrez: 4 1 2022
pubmed: 5 1 2022
medline: 6 1 2022
Statut: epublish

Résumé

In case of spinal cord compression behind the vertebral body, anterior cervical corpectomy and fusion (ACCF) proves to be a more feasible approach than cervical discectomy. The next step was the placement of an expandable titanium interbody in order to restore the vertebral height. The need for additional anterior plating with ACCF has been debatable and such technique has been evaluated by very few studies. The objective of the study is to evaluate radiographic and clinical outcomes in patients with multilevel degenerative cervical spine disease treated by stand-alone cages for anterior cervical corpectomy and fusion (ACCF). Thirty-one patients (66.5 ± 9.75 years, range 53-85 years) were analyzed. Visual Analog Scale (VAS) and the 10-item Neck Disability Index (NDI) were assessed preoperatively and during follow-up on a regular basis after surgery and after one year at least. Assessment of radiographic fusion, subsidence, and lordosis measurement of Global cervical lordosis (GCL); fusion site lordosis (FSL); the anterior interbody space height (ant. DSH); the posterior interbody space height (post. DSH); the distance of the cage to the posterior wall of the vertebral body (CD) were done retrospectively. Mean clinical and radiographic follow-up was 20.0 ± 4.39 months. VAS-neck (p = 0.001) and VAS-arm (p < 0.001) improved from preoperatively to postoperatively. The NDI improved at the final follow-up (p < 0.001). Neither significant subsidence of the cages nor significant loss of lordotic correction were seen. All patients showed a radiographic union of the surgically addressed segments at the last follow up. Application of a stand-alone expandable cage in the cervical spine after one or two-level ACCF without additional posterior fixation or anterior plating is a safe procedure that results in fusion. Neither significant subsidence of the cages nor significant loss of lordotic correction were seen. Retrospectively registered. According to the Decision of the ethics committee, Jena on 25th of July 2018, that this study doesn't need any registration.  https://www.laek-thueringen.de/aerzte/ethikkommission/registrierung/ .

Sections du résumé

BACKGROUND BACKGROUND
In case of spinal cord compression behind the vertebral body, anterior cervical corpectomy and fusion (ACCF) proves to be a more feasible approach than cervical discectomy. The next step was the placement of an expandable titanium interbody in order to restore the vertebral height. The need for additional anterior plating with ACCF has been debatable and such technique has been evaluated by very few studies. The objective of the study is to evaluate radiographic and clinical outcomes in patients with multilevel degenerative cervical spine disease treated by stand-alone cages for anterior cervical corpectomy and fusion (ACCF).
METHODS METHODS
Thirty-one patients (66.5 ± 9.75 years, range 53-85 years) were analyzed. Visual Analog Scale (VAS) and the 10-item Neck Disability Index (NDI) were assessed preoperatively and during follow-up on a regular basis after surgery and after one year at least. Assessment of radiographic fusion, subsidence, and lordosis measurement of Global cervical lordosis (GCL); fusion site lordosis (FSL); the anterior interbody space height (ant. DSH); the posterior interbody space height (post. DSH); the distance of the cage to the posterior wall of the vertebral body (CD) were done retrospectively. Mean clinical and radiographic follow-up was 20.0 ± 4.39 months.
RESULTS RESULTS
VAS-neck (p = 0.001) and VAS-arm (p < 0.001) improved from preoperatively to postoperatively. The NDI improved at the final follow-up (p < 0.001). Neither significant subsidence of the cages nor significant loss of lordotic correction were seen. All patients showed a radiographic union of the surgically addressed segments at the last follow up.
CONCLUSIONS CONCLUSIONS
Application of a stand-alone expandable cage in the cervical spine after one or two-level ACCF without additional posterior fixation or anterior plating is a safe procedure that results in fusion. Neither significant subsidence of the cages nor significant loss of lordotic correction were seen.
TRIAL REGISTRATION BACKGROUND
Retrospectively registered. According to the Decision of the ethics committee, Jena on 25th of July 2018, that this study doesn't need any registration.  https://www.laek-thueringen.de/aerzte/ethikkommission/registrierung/ .

Identifiants

pubmed: 34980062
doi: 10.1186/s12891-021-04883-5
pii: 10.1186/s12891-021-04883-5
pmc: PMC8725343
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20

Informations de copyright

© 2021. The Author(s).

Références

Neurosurgery. 2005 Oct;57(4):753-8; discussion 753-8
pubmed: 16239888
Adv Orthop. 2012;2012:307916
pubmed: 22496982
Medicine (Baltimore). 2016 Dec;95(49):e5437
pubmed: 27930523
J Korean Neurosurg Soc. 2010 Oct;48(4):335-41
pubmed: 21113361
Spine (Phila Pa 1976). 2010 Jul 15;35(16):1545-50
pubmed: 20581756
BMC Musculoskelet Disord. 2018 Apr 4;19(1):101
pubmed: 29615017
Indian J Orthop. 2012 Jan;46(1):92-8
pubmed: 22345814
Spine (Phila Pa 1976). 2003 Jan 1;28(1):46-51
pubmed: 12544955
Eur Spine J. 2003 Oct;12(5):513-6
pubmed: 12827473
J Clin Pathol. 1991 Dec;44(12):979-82
pubmed: 1791213
Spine (Phila Pa 1976). 2002 Jun 1;27(11):1168-75
pubmed: 12045513
N Engl J Med. 2005 Jul 28;353(4):392-9
pubmed: 16049211
Spine (Phila Pa 1976). 2005 Jun 15;30(12):1402-6
pubmed: 15959369
Int J Implant Dent. 2018 Jun 14;4(1):20
pubmed: 29900480
J Bone Joint Surg Am. 1997 Apr;79(4):523-32
pubmed: 9111396
J Am Acad Orthop Surg Glob Res Rev. 2018 Mar 23;2(3):e088
pubmed: 30211382
Spine (Phila Pa 1976). 1997 Nov 15;22(22):2622-4; discussion 2625
pubmed: 9399447
Neurospine. 2018 Mar;15(1):91-100
pubmed: 29656629
J Neurosurg Spine. 2006 Jun;4(6):447-53
pubmed: 16776355
Dental Press J Orthod. 2014 Jul-Aug;19(4):27-9
pubmed: 25279518
Eur Spine J. 2012 Jul;21(7):1374-82
pubmed: 22205113
J Neurosurg. 2002 Jan;96(1 Suppl):10-6
pubmed: 11795694
Spine (Phila Pa 1976). 2010 Mar 15;35(6):E206-11
pubmed: 20195201
Neurosurgery. 2006 Mar;58(3):502-8; discussion 502-8
pubmed: 16528190
Eur Spine J. 2012 May;21 Suppl 1:S90-3
pubmed: 22407262
J Neurosurg. 1999 Jan;90(1 Suppl):35-41
pubmed: 10413123
Spine (Phila Pa 1976). 2000 Apr 1;25(7):783-95
pubmed: 10751288
Eur Spine J. 2014 Jul;23(7):1472-9
pubmed: 24474645
Eur Spine J. 2012 Dec;21(12):2492-7
pubmed: 22842956
Eur Spine J. 2015 Aug;24(8):1621-30
pubmed: 25840781
Spine (Phila Pa 1976). 2011 Mar 15;36(6):463-8
pubmed: 21178831
J Neurosurg Spine. 2014 Jul;21(1):23-30
pubmed: 24980581
J Neurosurg. 2003 Jul;99(1 Suppl):91-7
pubmed: 12859067
BMC Musculoskelet Disord. 2014 Mar 19;15:91
pubmed: 24642209
Br J Neurosurg. 2010 Dec;24(6):633-40
pubmed: 20632875
J Spinal Disord Tech. 2009 Aug;22(6):385-91
pubmed: 19652562
Neurosurg Focus. 2003 Sep 15;15(3):E5
pubmed: 15347223

Auteurs

Mohamed H Tohamy (MH)

Spine Unit, Martin-Ulbrich-Haus Rothenburg, Horkaer Str. 15-21, 02929, Rothenburg, Oberlausitz, Germany.
Spine Departement, Helios Klinikum Erfurt, Nordhäuser Str. 74, 99089, Erfurt, Germany.
Ligamenta Spine Center, Walter-Kolb-Street 9-11, 60594, Frankfurt am Main, Germany.

Georg Osterhoff (G)

Department of Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, Liebigstrasse 20, 04179, Leipzig, Germany.

Ahmed Shawky Abdelgawaad (AS)

Spine Departement, Helios Klinikum Erfurt, Nordhäuser Str. 74, 99089, Erfurt, Germany.
Department of Orthopedic and Trauma Surgery, Assiut University Hospitals, Assiut, Egypt.

Ali Ezzati (A)

Spine Departement, Helios Klinikum Erfurt, Nordhäuser Str. 74, 99089, Erfurt, Germany.

Christoph-E Heyde (CE)

Department of Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, Liebigstrasse 20, 04179, Leipzig, Germany. Christoph-Eckhard.Heyde@medizin.uni-leipzig.de.
Department of Orthopedics, Trauma and Plastic Surgery, University Hospital Leipzig, 04103, Leipzig, Germany. Christoph-Eckhard.Heyde@medizin.uni-leipzig.de.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH