Disposable stochastic sensors obtained by nanolayer deposition of copper, graphene, and copper-graphene composite on silk for the determination of isocitrate dehydrogenases 1 and 2.


Journal

Analytical and bioanalytical chemistry
ISSN: 1618-2650
Titre abrégé: Anal Bioanal Chem
Pays: Germany
ID NLM: 101134327

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 14 10 2021
accepted: 25 11 2021
revised: 30 10 2021
pubmed: 6 1 2022
medline: 19 2 2022
entrez: 5 1 2022
Statut: ppublish

Résumé

Three disposable stochastic sensors designed using nanolayer deposition of copper (Cu), graphene (GR), and copper-graphene (Cu-GR) composite on the silk textile, as substrate, were modified with chitosan (n=371-744), for biomedical analysis. Isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) served as model analytes for molecular recognition and quantification in biological samples such as whole blood and brain tumor tissue samples. The best sensitivities (3.77×10

Identifiants

pubmed: 34984507
doi: 10.1007/s00216-021-03807-5
pii: 10.1007/s00216-021-03807-5
doi:

Substances chimiques

Isoenzymes 0
Silk 0
Graphite 7782-42-5
Copper 789U1901C5
Isocitrate Dehydrogenase EC 1.1.1.41

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1797-1807

Informations de copyright

© 2022. Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Catalina Cioates Negut (C)

Laboratory of Electrochemistry and PATLAB, National Institute of Research for Electrochemistry and Condensed Matter, 202 Splaiul Independentei St., 060021, Bucharest, Romania.

Raluca-Ioana Stefan-van Staden (RI)

Laboratory of Electrochemistry and PATLAB, National Institute of Research for Electrochemistry and Condensed Matter, 202 Splaiul Independentei St., 060021, Bucharest, Romania. ralucavanstaden@gmail.com.

Marius Badulescu (M)

Low Temperature Plasma Laboratory, National Institute for Lasers, Plasma and Radiation Physics (NILPRP), 409 Atomistilor St., 077125, Magurele, Romania. marius.badulescu@inflpr.ro.

Bogdan Bita (B)

Low Temperature Plasma Laboratory, National Institute for Lasers, Plasma and Radiation Physics (NILPRP), 409 Atomistilor St., 077125, Magurele, Romania.
Faculty of Physics, University of Bucharest, 405 Atomistilor St., 077125, Magurele, Romania.

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