A 2-plane micro-computed tomographic alveolar bone measurement approach in mice.
Alveolar Bone Loss
Periodontitis
Porphyromonas Gingivalis
X-Ray Microtomography
Journal
Imaging science in dentistry
ISSN: 2233-7822
Titre abrégé: Imaging Sci Dent
Pays: Korea (South)
ID NLM: 101559249
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
11
03
2021
revised:
27
05
2021
accepted:
11
06
2021
entrez:
6
1
2022
pubmed:
7
1
2022
medline:
7
1
2022
Statut:
ppublish
Résumé
This study introduces a standardized 2-plane approach using 8 landmarks to assess alveolar bone levels in mice using micro-computed tomography. Bone level differences were described as distance from the cemento-enamel junction (CEJ) to alveolar bone crest (ABC) and as percentages of vertical bone height and vertical bone loss, comparing mice infected with Significant differences in the CEJ-to-ABC distance between Pg-infected mice and controls were found in the coronal plane (middle-lingual, mesiobuccal, and distolingual for the first molar; and mesiobuccal, middle-buccal, and distolingual for the second molar). In the sagittal plane, the distal measurement of the second molar was different. The middle-buccal, mesiobuccal, and distolingual sites of the first and second molars showed vertical bone loss relative to controls; the second molar middle-lingual site was also different. In the sagittal plane, the mesial sites of the first and second molars and the distal site of the second molar showed loss. Significantly different vertical bone height percentages were found for the mesial and distal sites of the second molar (sagittal plane) and the middle-lingual and distolingual sites of the first molar(coronal plane). A reliable, standardized technique for linear periodontal assessments in mice is described. Alveolar bone loss occurred mostly on the lingual surface of the coronal plane, which is often omitted in studies.
Identifiants
pubmed: 34987999
doi: 10.5624/isd.20210058
pmc: PMC8695470
doi:
Types de publication
Journal Article
Langues
eng
Pagination
389-398Informations de copyright
Copyright © 2021 by Korean Academy of Oral and Maxillofacial Radiology.
Déclaration de conflit d'intérêts
Conflicts of Interest: None
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