Psychological distress and experiences of Adolescents and Young Adults with cancer during the COVID-19 pandemic: A cross-sectional survey.
COVID-19
adolescent
cancer
mental health
oncology
pandemic
psycho-oncology
psychological distress
young adult
Journal
Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
16
10
2021
received:
17
07
2021
accepted:
26
10
2021
pubmed:
7
1
2022
medline:
13
4
2022
entrez:
6
1
2022
Statut:
ppublish
Résumé
This study investigated prevalence of psychological distress, factors associated with distress, and experiences of Adolescents and Young Adults (AYAs) with cancer during the COVID-19 pandemic. It also compared distress in this group to previously surveyed Canadian AYAs with cancer in 2018 by the Young Adults with Cancer in their Prime (YACPRIME) study. A cross-sectional, online, self-administered survey of AYAs diagnosed with cancer between 15 and 39 years of age was conducted. Psychological distress was measured by the Kessler Psychological Distress Scale (K10). Associations between variables and high psychological distress (K10 ≥ 25), and comparison of prevalence of psychological distress with the YACPRIME study were done using multivariable logistic regression. Summative qualitative content analysis analyzed participant experiences during this pandemic. We included 805 participants. High psychological distress was present in over two-thirds of the group (68.0%; 95% CI, 64.7%-71.2%). Employment impact during pandemic (AOR (adjusted odds ratio), 2.16; 95% CI, 1.41-3.31) and hematologic malignancy (AOR, 1.76; 95% CI 1.08-2.97) were associated with higher psychological distress, while older age [AOR, 0.95; 95% CI, 0.92-0.99] and personal income < $40,000 (AOR, 0.38; 95% CI, 0.24-0.58) were associated with lower distress. Adjusted odds of experiencing psychological distress among AYAs with cancer during pandemic compared to pre-pandemic years was 1.85 (95% CI: 1.36-2.53). Overarching themes of pandemic experiences included: inferior quality of life, impairment of cancer care, COVID-19 related concerns and extreme social isolation. AYAs diagnosed with cancer are experiencing high psychological distress during this pandemic. Distress screening and evidence-based interventions to alleviate distress are essential.
Sections du résumé
BACKGROUND
This study investigated prevalence of psychological distress, factors associated with distress, and experiences of Adolescents and Young Adults (AYAs) with cancer during the COVID-19 pandemic. It also compared distress in this group to previously surveyed Canadian AYAs with cancer in 2018 by the Young Adults with Cancer in their Prime (YACPRIME) study.
METHODS
A cross-sectional, online, self-administered survey of AYAs diagnosed with cancer between 15 and 39 years of age was conducted. Psychological distress was measured by the Kessler Psychological Distress Scale (K10). Associations between variables and high psychological distress (K10 ≥ 25), and comparison of prevalence of psychological distress with the YACPRIME study were done using multivariable logistic regression. Summative qualitative content analysis analyzed participant experiences during this pandemic.
RESULTS
We included 805 participants. High psychological distress was present in over two-thirds of the group (68.0%; 95% CI, 64.7%-71.2%). Employment impact during pandemic (AOR (adjusted odds ratio), 2.16; 95% CI, 1.41-3.31) and hematologic malignancy (AOR, 1.76; 95% CI 1.08-2.97) were associated with higher psychological distress, while older age [AOR, 0.95; 95% CI, 0.92-0.99] and personal income < $40,000 (AOR, 0.38; 95% CI, 0.24-0.58) were associated with lower distress. Adjusted odds of experiencing psychological distress among AYAs with cancer during pandemic compared to pre-pandemic years was 1.85 (95% CI: 1.36-2.53). Overarching themes of pandemic experiences included: inferior quality of life, impairment of cancer care, COVID-19 related concerns and extreme social isolation.
CONCLUSION
AYAs diagnosed with cancer are experiencing high psychological distress during this pandemic. Distress screening and evidence-based interventions to alleviate distress are essential.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
631-640Informations de copyright
© 2021 John Wiley & Sons Ltd.
Références
Alwan NA, Burgess RA, Ashworth S, et al. Scientific consensus on the COVID-19 pandemic: we need to act now. Lancet. 2020;396(10260):e71-e72.
Detsky AS, Bogoch II. Bogoch II. COVID-19 in Canada: experience and response. J Am Med Assoc. 2020;324(8):743-744.
Berlin A, Lovas M, Truong T, et al. Implementation and outcomes of virtual care across a tertiary cancer center during COVID-19. JAMA Oncology. 2021;7(4):597-602.
Blumenthal D, Fowler EJ, Abrams M, Collins SR. Covid-19 - implications for the health care system. N. Engl J Med. 2020;383(15):1483-1488.
Government of Canada SC. Canadians report lower self-perceived mental health during the COVID-19 pandemic. Accessed August 24, 2021.Published April 24, 2020. https://www150.statcan.gc.ca/n1/pub/45-28-0001/2020001/article/00003-eng.htm
Singh S, Roy D, Sinha K, Parveen S, Sharma G, Joshi G. Impact of COVID-19 and lockdown on mental health of children and adolescents: a narrative review with recommendations. Psychiatr Res. 2020;293:113429.
Lane B, Fowler K, Eaton G, Chalifour K, Garland SN. Prevalence and factors associated with high levels of distress in young adult cancer survivors compared to matched peers. Support Care Cancer. 2021;29(5):2653-2662.
Fung M, Babik JM. COVID-19 in immunocompromised hosts: what we know so far. Clin Infect Dis. 2021;72(2):340-350.
Jazieh AR, Akbulut H, Curigliano G, et al. Impact of the COVID-19 pandemic on cancer care: a global collaborative study. JCO Glob Oncol. 2020(6):1428-1438.
Košir U, Loades M, Wild J, et al. The impact of COVID-19 on the cancer care of adolescents and young adults and their well-being: results from an online survey conducted in the early stages of the pandemic. Cancer. 2020;126(19):4414-4422.
Younger E, Smrke A, Lidington E, et al. Health-related quality of life and experiences of sarcoma patients during the COVID-19 pandemic. Cancers. 2020;12(8).
Hanghoj S, Pappot N, Hjerming M, Taarnhoj GA, Boisen KA, Pappot H. Experiences of social isolation during the COVID-19 lockdown among adolescents and young adult cancer patients and survivors. J Adolesc Young Adult Oncol. 2021;10(2):142-147.
Shanahan L, Steinhoff A, Bechtiger L, et al. Emotional distress in young adults during the COVID-19 pandemic: evidence of risk and resilience from a longitudinal cohort study. Psychol Med. 2020:1-10.
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research Electronic Data Capture (REDCap) - a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inf. 2009;42(2):377-381.
Andrews G, Slade T. Interpreting scores on the kessler psychological distress scale (K10). Aust N Z J Publ Health. 2001;25(6):494-497.
Clover K, Carter GL, Mackinnon A, Adams C. Is my patient suffering clinically significant emotional distress? Demonstration of a probabilities approach to evaluating algorithms for screening for distress. Support Care Cancer. 2009;17(12):1455-1462.
R Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2021. https://www.R-project.org/
Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277-1288.
Kolb S. Grounded theory and the constant comparative method: valid research strategies for educators. J Emerg Trends Educ Res Policy Stud. 2012;3:83-86.
Dedoose Version 8.3.47, Web Application for Managing, Analyzing, and Presenting Qualitative and Mixed Method Research Data (2021). Los Angeles, CA: SocioCultural Research Consultants, LLC. www.dedoose.com
Pierce M, Hope H, Ford T, et al. Mental health before and during the COVID-19 pandemic: a longitudinal probability sample survey of the UK population. Lancet Psychiatry. 2020;7(10):883-892.
COVID-19 National Survey Dashboard. CAMH. Accessed June 1 2021 Retrieved from. https://www.camh.ca/en/health-info/mental-health-and-covid-19/covid-19-national-survey
Duan Y, Wang L, Sun Q, et al. Prevalence and determinants of psychological distress in adolescent and young adult patients with cancer: a multicenter survey. Asia Pac J Oncol Nurs. 2021;8(3):314-321.
Xie J, Ding S, He S, Duan Y, Yi K, Zhou J. A prevalence study of psychosocial distress in adolescents and young adults with cancer. Cancer Nurs. 2017;40(3):217-223.
Smith AW, Bellizzi KM, Keegan THM, et al. Health-related quality of life of adolescent and young adult patients with cancer in the United States: the Adolescent and Young Adult Health Outcomes and Patient Experience study. J Clin Oncol. 2013;31(17):2136-2145.
Willan J, King AJ, Hayes S, Collins GP, Peniket A. Care of haematology patients in a COVID-19 epidemic. Br J Haematol. 2020;189(2):241-243.
Government of Canada SC. The daily - labour force survey, January 2021. Published February 5, 2021. Accessed August 28 2021. https://www150.statcan.gc.ca/n1/daily-quotidien/210205/dq210205a-eng.htm
Mahon, KN, Garland, SN, Eaton, G, et al. The financial impact of cancer on Canadian young adults. J Cancer Surviv. Published online February 14, 2021.
Cornell S, Nickel B, Cvejic E, et al. What positives can be taken from the COVID-19 pandemic in Australia? medRxiv. 2020. https://doi.org/10.1101/2020.12.10.20247346. https://www.medrxiv.org/content/10.1101/2020.12.10.20247346v1