EP
chronic kidney disease
human precision-cut kidney slices
prostaglandin E2 EP1 receptor
renal fibrosis
Journal
Acta physiologica (Oxford, England)
ISSN: 1748-1716
Titre abrégé: Acta Physiol (Oxf)
Pays: England
ID NLM: 101262545
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
revised:
09
12
2021
received:
02
07
2021
accepted:
01
01
2022
pubmed:
7
1
2022
medline:
30
4
2022
entrez:
6
1
2022
Statut:
ppublish
Résumé
Renal fibrosis is a major driver of chronic kidney disease, yet current treatment strategies are ineffective in attenuating fibrogenesis. The cyclooxygenase/prostaglandin system plays a key role in renal injury and holds great promise as a therapeutic target. Here, we used a translational approach to evaluate the role of the PGE The anti-fibrotic efficacy of a selective EP EP This study highlights the EP
Identifiants
pubmed: 34989478
doi: 10.1111/apha.13780
pmc: PMC9286353
doi:
Substances chimiques
Transforming Growth Factor beta
0
Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
19395-87-0
Collagen
9007-34-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13780Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022 The Authors. Acta Physiologica published by John Wiley & Sons Ltd on behalf of Scandinavian Physiological Society.
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