Acrylamide levels in smoke from conventional cigarettes and heated tobacco products and exposure assessment in habitual smokers.

Acrylamide / toxicity Carcinogens / analysis Humans Smokers Nicotiana Tobacco Products
Acrylamide Cigarettes Heated tobacco Risk assessment Smokers

Journal

Environmental research
ISSN: 1096-0953
Titre abrégé: Environ Res
Pays: Netherlands
ID NLM: 0147621

Informations de publication

Date de publication:
15 05 2022
Historique:
received: 14 10 2021
revised: 29 12 2021
accepted: 30 12 2021
pubmed: 7 1 2022
medline: 2 4 2022
entrez: 6 1 2022
Statut: ppublish

Résumé

Acrylamide (AA) is a neurotoxic, genotoxic, and carcinogenic compound developed during heating at high temperatures. Foods such as potatoes, biscuits, bread and coffee are the main foodstuffs containing AA. Cigarette smoke may be a significant additional source of exposure. However, AA content may vary among different types of cigarettes. The study aimed to evaluate the AA content in conventional cigarettes (CC) and heated tobacco products (HTP) and its resulting exposure through their use. AA levels from the two types of cigarettes were determined by GC-MS and the daily exposure to AA was also ascertained. The margin of exposure (MOE) was calculated for neurotoxic and carcinogenic risk based on benchmark dose lower confidence limit for a 10% response (BMDL

Identifiants

DOI: 10.1016/j.envres.2021.112659 PMID: 34990604
pubmed: 34990604
pii: S0013-9351(21)01960-5
doi: 10.1016/j.envres.2021.112659
pii:
doi:

Substances chimiques

Carcinogens 0
Acrylamide 20R035KLCI

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112659

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Francesco Esposito (F)

Department of Public Health, University of Naples "Federico II", via Sergio Pansini, 5 - 80131 Naples, Italy. Electronic address: francesco.esposito4@unina.it.

Jonathan Squillante (J)

Department of Agricultural Sciences, University of Naples "Federico II", via Università, 100 - 80055 Portici, Naples, Italy.

Agata Nolasco (A)

Department of Agricultural Sciences, University of Naples "Federico II", via Università, 100 - 80055 Portici, Naples, Italy.

Paolo Montuori (P)

Department of Public Health, University of Naples "Federico II", via Sergio Pansini, 5 - 80131 Naples, Italy.

Pasquale Giuseppe Macrì (PG)

Area Dipartimentale Medicina Legale e Gestione Della Responsabilità Sanitaria Az. USL Toscana Sud Est, Siena, Arezzo, Grosseto, Italy.

Teresa Cirillo (T)

Department of Agricultural Sciences, University of Naples "Federico II", via Università, 100 - 80055 Portici, Naples, Italy.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acrylates › Acrylamides › Acrylamide › Acrylamide levels in smoke from conventional...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Noxas › Cancérogènes › Acrylamide levels in smoke from conventional...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Acrylamide levels in smoke from conventional...
questionsmedicales.fr › Personnes › Fumeurs › Acrylamide levels in smoke from conventional...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Dispositifs pour fumer › Produits du tabac › Acrylamide levels in smoke from conventional...