Challenges for Estimating the Global Prevalence of Micronutrient Deficiencies and Related Disease Burden: A Case Study of the Global Burden of Disease Study.

deficiency global burden of disease iodine iron micronutrient prevalence vitamin A zinc

Journal

Current developments in nutrition
ISSN: 2475-2991
Titre abrégé: Curr Dev Nutr
Pays: United States
ID NLM: 101717957

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 01 09 2021
revised: 05 11 2021
accepted: 16 11 2021
entrez: 7 1 2022
pubmed: 8 1 2022
medline: 8 1 2022
Statut: epublish

Résumé

Information on the prevalence of micronutrient deficiencies is needed to determine related disease burden; underpin evidence-based advocacy; and design, deliver, and monitor safe, effective interventions. Assessing the global prevalence of deficiency requires a valid micronutrient status biomarker with an appropriate cutoff to define deficiency and relevant data from representative surveys across multiple locations and years. The Global Burden of Disease Study includes prevalence estimates for iodine, iron, zinc, and vitamin A deficiencies, for which recommended biomarkers and appropriate deficiency cutoffs exist. Because representative survey data are lacking, only retinol concentration is used to model vitamin A deficiency, and proxy indicators are used for the other micronutrients (goiter for iodine, hemoglobin for iron, and dietary food adequacy for zinc). Because of data limitations, complex statistical modeling is required to produce current estimates, relying on assumptions and proxies that likely understate the extent of micronutrient deficiencies and the consequent global health burden.

Identifiants

pubmed: 34993390
doi: 10.1093/cdn/nzab141
pii: nzab141
pmc: PMC8728001
doi:

Types de publication

Journal Article

Langues

eng

Pagination

nzab141

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.

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Auteurs

Sonja Y Hess (SY)

Institute for Global Nutrition and Department of Nutrition, University of California, Davis, Davis, CA, USA.

Alexander C McLain (AC)

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Edward A Frongillo (EA)

Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Ashkan Afshin (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Nicholas J Kassebaum (NJ)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Saskia J M Osendarp (SJM)

The Micronutrient Forum, Washington, DC, USA.

Reed Atkin (R)

The Micronutrient Forum, Washington, DC, USA.

Rahul Rawat (R)

Bill & Melinda Gates Foundation, Seattle, WA, USA.

Kenneth H Brown (KH)

Institute for Global Nutrition and Department of Nutrition, University of California, Davis , Davis, CA, USA.

Classifications MeSH