Quantifying Tumor and Vasculature Deformations during Laryngoscopy.

Intraoperative deformation Laryngeal cancer Transoral surgery Tumor deformation Vasculature deformation

Journal

Annals of biomedical engineering
ISSN: 1573-9686
Titre abrégé: Ann Biomed Eng
Pays: United States
ID NLM: 0361512

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 26 07 2021
accepted: 17 11 2021
pubmed: 8 1 2022
medline: 5 4 2022
entrez: 7 1 2022
Statut: ppublish

Résumé

Retractors and scopes used in head and neck surgery to provide adequate surgical exposure also deform critical structures in the region. Surgeons typically use preoperative imaging to plan and guide their tumor resections, however the large tissue deformation resulting from placement of retractors and scopes reduces the utility of preoperative imaging as a reliable roadmap. We quantify the extent of tumor and vasculature deformation in patients with tumors of the larynx and pharynx undergoing diagnostic laryngoscopy. A mean tumor displacement of 1.02 cm was observed between the patients' pre- and intra-operative states. Mean vasculature displacement at key bifurcation points was 0.99 cm. Registration to the hyoid bone can reduce tumor displacement to 0.67 cm and improve carotid stem angle deviations but increase overall vasculature displacement. The large deformation results suggest limitations in reliance on preoperative imaging and that using specific landmarks intraoperatively or having more intraoperative information could help to compensate for these deviations and ultimately improve surgical success.

Identifiants

pubmed: 34993696
doi: 10.1007/s10439-021-02896-8
pii: 10.1007/s10439-021-02896-8
pmc: PMC9035291
mid: NIHMS1794971
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

94-107

Subventions

Organisme : NIBIB NIH HHS
ID : T32EB013180
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001086
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB013180
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1TR001096
Pays : United States
Organisme : NCATS NIH HHS
ID : L30 TR001096
Pays : United States

Informations de copyright

© 2021. Biomedical Engineering Society.

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Auteurs

Xiaotian Wu (X)

Gordon Center for Medical Imaging at Massachusetts General Hospital and Harvard Medical School, 13th St, CNY149-5212, Charlestown, MA, 02129, USA. Xwu23@mgh.harvard.edu.

David A Pastel (DA)

Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.

Rihan Khan (R)

Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.

Clifford J Eskey (CJ)

Department of Radiology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.
Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.

Yuan Shi (Y)

Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.

Michael Sramek (M)

Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.

Joseph A Paydarfar (JA)

Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.
Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Section of Otolaryngology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH, 03756, USA.

Ryan J Halter (RJ)

Geisel School of Medicine at Dartmouth College, 1 Rope Ferry Rd., Hanover, NH, 03755, USA.
Thayer School of Engineering at Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.

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Classifications MeSH