Pancreatic duct rupture associated with high-grade pancreatic intraepithelial neoplasia treated by radical resection: a case report.
High-grade pancreatic intraepithelial neoplasia
Pancreatic cancer
Pancreatic duct rupture
Journal
Clinical journal of gastroenterology
ISSN: 1865-7265
Titre abrégé: Clin J Gastroenterol
Pays: Japan
ID NLM: 101477246
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
14
10
2021
accepted:
27
12
2021
pubmed:
8
1
2022
medline:
7
6
2022
entrez:
7
1
2022
Statut:
ppublish
Résumé
We here report a case of pancreatic duct rupture associated with high-grade pancreatic intraepithelial neoplasia treated by radical resection. A 71-year-old man presented to our hospital because of abdominal bloating. Diagnoses of early-stage pancreatic body cancer with pancreatic duct rupture, pancreatic ascites, and formation of a pseudocyst were made on the basis of blood tests, multidetector dynamic computed tomography, endoscopic ultrasonography, magnetic resonance cholangiopancreatography, and endoscopic retrograde cholangiopancreatography. After achieving control of the ascites by placement of a pancreatic duct stent and aspiration of the pseudocyst, distal pancreatectomy with D2 lymph node dissection was performed. Intraoperative cytologic examination of the ascites was negative. The pathological diagnosis was high-grade pancreatic intraepithelial neoplasia in the pancreatic body. The branched pancreatic duct was occluded and dilated by acute inflammation around the pancreatic neoplasm, the inflammation being in the region of the dilated branched pancreatic duct and having caused its rupture. To the best of our knowledge, this is the first published report of pancreatic duct rupture associated with high-grade pancreatic intraepithelial neoplasia.
Identifiants
pubmed: 34994960
doi: 10.1007/s12328-021-01587-0
pii: 10.1007/s12328-021-01587-0
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
662-667Informations de copyright
© 2022. Japanese Society of Gastroenterology.
Références
Kimura W, Sata N, Nakayama H, et al. Pancreatic carcinoma accompanied by pseudocyst: report of two cases. J Gastroenterol. 1994;29:786–91.
doi: 10.1007/BF02349289
Bozymski EM, Orlando RC, Holt JW 3rd. Traumatic disruption of the pancreatic duct demonstrated by endoscopic retrograde pancreatography. Trauma. 1981;21:244–5.
Jang JW, Kim MH, Oh D, et al. Factors and outcomes associated with pancreatic duct disruption in patients with acute necrotizing pancreatitis. Pancreatology. 2016;16:958–65.
doi: 10.1016/j.pan.2016.09.009
Inagi E, Shimodan S, Amizuka H, et al. Pancreatic cancer initially presenting with a pseudocyst at the splenic flexure. Pathol Int. 2006;56:558–62.
doi: 10.1111/j.1440-1827.2006.02006.x
Yamaguchi T, Takahashi H, Kagawa R, et al. Huge pseudocyst of the pancreas caused by poorly differentiated invasive ductal adenocarcinoma with osteoclast-like giant cells: report of a case. Hepatogastroenterology. 2007;54:599–601.
pubmed: 17523330
Liu A, Zeh HJ, Boone BA. Pancreatic cancer presenting as a pancreatic duct disruption. Case Rep Surg. 2019;2019:6381249.
pubmed: 31263623
pmcid: 6556244
Japan Pancreas Society. Classification of pancreatic carcinoma, 4th English edn. 2017.