Development and Characterization of a Fluorescent Ligand for Leukotriene B4 Receptor 2 in Cells and Tissues.

Animals Binding Sites CHO Cells Cricetinae Cricetulus Drug Design Fatty Acids, Unsaturated / chemistry Fluorescent Dyes / chemical synthesis Humans Kinetics Ligands Mice Microscopy, Fluorescence Protein Binding Receptors, Leukotriene B4 / agonists Skin / metabolism

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
10 02 2022
Historique:
pubmed: 8 1 2022
medline: 23 2 2022
entrez: 7 1 2022
Statut: ppublish

Résumé

The leukotriene B4 receptor 2 (BLT2) is a G-protein coupled receptor activated by 12(

Identifiants

DOI: 10.1021/acs.jmedchem.1c01589 PMID: 34995452
pubmed: 34995452
doi: 10.1021/acs.jmedchem.1c01589
doi:

Substances chimiques

Fatty Acids, Unsaturated 0
Fluorescent Dyes 0
Ligands 0
Receptors, Leukotriene B4 0
12-hydroxy-5,8,10-heptadecatrienoic acid 50683-78-8

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2023-2034

Auteurs

Jan Heering (J)

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, D-60596 Frankfurt, Germany.
ORCID: 0000-0002-4922-1993

Victor Hernandez-Olmos (V)

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, D-60596 Frankfurt, Germany.

Niklas Ildefeld (N)

Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.

Ting Liu (T)

Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.

Anja Kaiser (A)

Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.

Zumer Naeem (Z)

Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, D-60596 Frankfurt am Main, Germany.

Timo Frömel (T)

Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, D-60596 Frankfurt am Main, Germany.

Ingrid Fleming (I)

Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, D-60596 Frankfurt am Main, Germany.

Dieter Steinhilber (D)

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, D-60596 Frankfurt, Germany.
Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.

Ewgenij Proschak (E)

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, D-60596 Frankfurt, Germany.
Institute of Pharmaceutical Chemistry, Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.
ORCID: 0000-0003-1961-1859

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Development and Characterization of a...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Development and Characterization of a...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › Development and Characterization of a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Development and Characterization of a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › Development and Characterization of a...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Conception de médicament › Development and Characterization of a...
questionsmedicales.fr › Lipides › Acides gras › Acides gras insaturés › Development and Characterization of a...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Development and Characterization of a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Development and Characterization of a...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Development and Characterization of a...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Development and Characterization of a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Development and Characterization of a...
questionsmedicales.fr › Techniques d'investigation › Microscopie de fluorescence › Development and Characterization of a...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Development and Characterization of a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs aux éicosanoïdes › Récepteurs aux leucotriènes › Récepteurs aux leucotriènes B4 › Development and Characterization of a...
questionsmedicales.fr › Système tégumentaire › Peau › Development and Characterization of a...