Plasma Homocysteine in Behcet's Disease: A Systematic Review and Meta-Analysis.
Journal
Thrombosis and haemostasis
ISSN: 2567-689X
Titre abrégé: Thromb Haemost
Pays: Germany
ID NLM: 7608063
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
pubmed:
8
1
2022
medline:
20
8
2022
entrez:
7
1
2022
Statut:
ppublish
Résumé
To evaluate the relevance of plasma homocysteine (HC) in Behcet's disease (BD) and its clinical manifestations. Systematic review of EMBASE and PubMed databases according to PRISMA guidelines from inception to July 2021; random-effects meta-analyses for continuous outcomes. The search strategy retrieved 48 case-control (2,669 BD and 2,245 control participants) and 5 cohort studies (708 BD participants). Plasma HC was higher in BD than in controls ( Although causality cannot be inferred, the consistency of the elevation of plasma HC in BD, particularly in patients with active disease, with vascular and ocular involvement suggests an intrinsic involvement of HC in these clinical manifestations.
Identifiants
pubmed: 34996122
doi: 10.1055/s-0041-1740637
doi:
Substances chimiques
Homocysteine
0LVT1QZ0BA
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1209-1220Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
None declared.