Noninvasive Ventilation in the Management of Respiratory Failure Due to COVID-19 Infection: Experience From a Resource-Limited Setting.


Journal

Mayo Clinic proceedings
ISSN: 1942-5546
Titre abrégé: Mayo Clin Proc
Pays: England
ID NLM: 0405543

Informations de publication

Date de publication:
01 2022
Historique:
received: 25 05 2021
revised: 16 09 2021
accepted: 05 10 2021
entrez: 8 1 2022
pubmed: 9 1 2022
medline: 21 1 2022
Statut: ppublish

Résumé

To study the role of noninvasive ventilation (NIV) in Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV2) related acute respiratory failure (C-ARF). Patients with C-ARF managed on NIV were categorized as NIV success or failure (death or intubation). Factors associated with failure were explored using regression analysis and expressed as odds ratio (OR) with 95% CI. Between April 1, 2020, and September 15, 2020, a total of 286 patients with a mean ± SD age of 53.1±11.6 years and Acute Physiology and Chronic Health Evaluation II score of 11.1±5.5 were initiated on NIV. Of the 182 patients (63.6%) successfully managed on NIV alone, 118 had moderate or severe acute respiratory distress syndrome. When compared with NIV success, NIV failure was associated with lower admission PaO Noninvasive ventilation can be used successfully in C-ARF. Illness severity and need for non-respiratory organ support predict NIV failure.

Identifiants

pubmed: 34996563
pii: S0025-6196(21)00773-4
doi: 10.1016/j.mayocp.2021.10.002
pmc: PMC8511655
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

31-45

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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Auteurs

Binila Chacko (B)

Medical Intensive Care Unit, Christian Medical College, Vellore, India. Electronic address: binilachacko@gmail.com.

Lovely Thomas (L)

Medical Intensive Care Unit, Christian Medical College, Vellore, India.

Roshni Sharma (R)

Medical Intensive Care Unit, Christian Medical College, Vellore, India.

Bijesh Yadav (B)

Department of Biostatistics, Christian Medical College, Vellore, India.

Lakshmanan Jeyaseelan (L)

Department of Biostatistics, Mohammed Bin Rashid University, COM, Dubai, UAE.

Ashwin O Arul (AO)

Respiratory Medicine, Christian Medical College, Vellore, India.

Punitha Victor (P)

Medicine Unit 1, Christian Medical College, Vellore, India.

Vignesh K Chandiraseharan (VK)

Medicine 2, Christian Medical College, Vellore, India.

Audrin Lenin (A)

Medicine 3, Christian Medical College, Vellore, India.

Ronald A B Carey (RAB)

Medicine 4, Christian Medical College, Vellore, India.

Jonathan A J Jayakaran (JAJ)

Medicine 5, Christian Medical College, Vellore, India.

Rajiv K Krishnaswami (RK)

Infectious Diseases, Christian Medical College, Vellore, India.

John Victor Peter (JV)

Medical Intensive Care Unit, Christian Medical College, Vellore, India.

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