Short interval intracortical inhibition: Variability of amplitude and threshold-tracking measurements with 6 or 10 stimuli per point.
Parallel threshold-tracking versus conventional TMS
SICI variability
Short-interval intracortical inhibition
Journal
Neurophysiologie clinique = Clinical neurophysiology
ISSN: 1769-7131
Titre abrégé: Neurophysiol Clin
Pays: France
ID NLM: 8804532
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
20
09
2021
revised:
18
10
2021
accepted:
16
11
2021
pubmed:
11
1
2022
medline:
20
4
2022
entrez:
10
1
2022
Statut:
ppublish
Résumé
Reduced short-interval intracortical inhibition (SICI) in motor neuron disease has been demonstrated by amplitude changes (A-SICI) and threshold-tracking (T-SICI) using 10 stimuli per inter-stimulus interval (ISI). To test whether fewer stimuli would suffice, A-SICI and T-SICI were recorded twice from 30 healthy subjects using 6 and 10 stimuli per ISI. Using fewer stimuli increased mean A-SICI variances by 23.8% but the 7.3% increase in T-SICI variance was not significant. We conclude that our new parallel threshold-tracking SICI protocol, with 6 stimuli per ISI, can reduce time and stimulus numbers by 40% without appreciable loss of accuracy.
Identifiants
pubmed: 35000804
pii: S0987-7053(21)00133-7
doi: 10.1016/j.neucli.2021.11.006
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
170-173Subventions
Organisme : Medical Research Council
ID : MR/K015222/1
Pays : United Kingdom
Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration Competing of Interest HB and JH receive from UCL shares of the royalties for sales of the Qtrac software used in this study. HB, HT, BC, and MK are shareholders of QTMS Science Ltd., which licences the QTMSG-12 recording protocols used. GS has no potential conflict of interest to declare.