Development of an
Animals
Antibodies, Monoclonal
/ immunology
Antibodies, Neutralizing
/ immunology
Antibodies, Viral
/ immunology
COVID-19
/ pathology
Cell Line
Disease Models, Animal
Fluorescent Antibody Technique
/ methods
Humans
Lung
/ pathology
Macaca mulatta
Proof of Concept Study
SARS-CoV-2
/ growth & development
Spike Glycoprotein, Coronavirus
/ immunology
Viral Load
/ methods
Virus Replication
/ physiology
COVID-19
SARS-CoV-2
antibodies
antibody probes
nonhuman primates
rhesus macaque
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2021
2021
Historique:
received:
05
11
2021
accepted:
10
12
2021
entrez:
10
1
2022
pubmed:
11
1
2022
medline:
19
1
2022
Statut:
epublish
Résumé
Infection with the novel coronavirus, SARS-CoV-2, results in pneumonia and other respiratory symptoms as well as pathologies at diverse anatomical sites. An outstanding question is whether these diverse pathologies are due to replication of the virus in these anatomical compartments and how and when the virus reaches those sites. To answer these outstanding questions and study the spatiotemporal dynamics of SARS-CoV-2 infection a method for tracking viral spread
Identifiants
pubmed: 35003140
doi: 10.3389/fimmu.2021.810047
pmc: PMC8739270
doi:
Substances chimiques
Antibodies, Monoclonal
0
Antibodies, Neutralizing
0
Antibodies, Viral
0
CR3022
0
Spike Glycoprotein, Coronavirus
0
spike protein, SARS-CoV-2
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
810047Subventions
Organisme : NIH HHS
ID : K01 OD026571
Pays : United States
Organisme : NIH HHS
ID : P51 OD011104
Pays : United States
Organisme : NIAID NIH HHS
ID : R37 AI094595
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007476
Pays : United States
Informations de copyright
Copyright © 2021 Madden, Arif, Becker, McRaven, Carias, Lorenzo-Redondo, Xiao, Midkiff, Blair, Potter, Martin-Sancho, Dodson, Martinelli, Todd, Villinger, Chanda, Aye, Roy, Roederer, Lewis, Veazey and Hope.
Déclaration de conflit d'intérêts
Authors AD and ML are employed by Bioqual, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Nat Rev Microbiol. 2021 Mar;19(3):155-170
pubmed: 33116300
Mol Cell. 2021 Jun 17;81(12):2656-2668.e8
pubmed: 33930332
Science. 2020 May 8;368(6491):630-633
pubmed: 32245784
Sci Rep. 2017 Dec 4;7(1):16878
pubmed: 29203879
Nat Commun. 2020 Nov 27;11(1):6078
pubmed: 33247138
Andrology. 2021 Jul;9(4):1053-1059
pubmed: 33742540
Cancer. 2000 Sep 1;89(5):1134-44
pubmed: 10964344
Front Microbiol. 2018 Aug 23;9:1996
pubmed: 30190717
Virus Evol. 2021 Sep 29;7(2):veab078
pubmed: 34642605
Mol Imaging Biol. 2020 Feb;22(1):115-123
pubmed: 31004274
Nature. 2020 Mar;579(7798):270-273
pubmed: 32015507
EJNMMI Res. 2021 Jan 21;11(1):8
pubmed: 33475899
Science. 2020 Aug 14;369(6505):818-823
pubmed: 32616673
J Nucl Med. 2019 Jan;60(1):23-25
pubmed: 30573641
Science. 2021 Aug 13;373(6556):818-823
pubmed: 34016740
JAMA. 2020 Nov 10;324(18):1899-1901
pubmed: 32970139
Cell Mol Immunol. 2021 Feb;18(2):487-489
pubmed: 33318629
N Engl J Med. 2020 Oct 15;383(16):1544-1555
pubmed: 32722908
Cells. 2019 Oct 21;8(10):
pubmed: 31640299
Eur J Nucl Med Mol Imaging. 2007 Sep;34(9):1376-87
pubmed: 17277931
Nat Biomed Eng. 2019 May;3(5):371-380
pubmed: 30936432
Mol Cell. 2020 May 21;78(4):779-784.e5
pubmed: 32362314
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
J Surg Res. 2009 Jan;151(1):68-73
pubmed: 18599080
Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33
pubmed: 26787852
Chem Rev. 2020 Apr 22;120(8):3787-3851
pubmed: 32202104
ChemMedChem. 2018 Dec 6;13(23):2466-2478
pubmed: 30246488
Nat Methods. 2015 May;12(5):427-32
pubmed: 25751144
J Am Soc Nephrol. 2020 Jun;31(6):1157-1165
pubmed: 32345702
J Immunol Methods. 2017 Nov;450:66-72
pubmed: 28780040
Int J Mol Sci. 2021 Jan 28;22(3):
pubmed: 33525632
Theranostics. 2017 Aug 11;7(14):3398-3414
pubmed: 28912884
J Nucl Med. 2013 Nov;54(11):1869-75
pubmed: 24029656
Cell Host Microbe. 2020 Sep 9;28(3):445-454.e6
pubmed: 32585135
Gut. 2020 Jun;69(6):997-1001
pubmed: 32241899
Front Immunol. 2020 Oct 07;11:576622
pubmed: 33117378
Am J Pathol. 2021 Feb;191(2):274-282
pubmed: 33171111
J Nucl Med. 2019 Oct;60(10):1467-1473
pubmed: 30877181
Nature. 2021 Mar;591(7851):639-644
pubmed: 33461210
Bone Res. 2018 Apr 25;6:13
pubmed: 29707402
Mucosal Immunol. 2018 May;11(3):932-946
pubmed: 29346349
Science. 2020 May 29;368(6494):1012-1015
pubmed: 32303590
Nat Commun. 2021 May 4;12(1):2506
pubmed: 33947851
World J Mens Health. 2021 Jul;39(3):466-469
pubmed: 33988001
Front Cell Infect Microbiol. 2021 Nov 18;11:753444
pubmed: 34869063
Allergy. 2021 Oct 12;:
pubmed: 34637150
Eur Heart J. 2020 Oct 14;41(39):3827-3835
pubmed: 32968776
PLoS One. 2012;7(1):e30690
pubmed: 22303450
Science. 2020 Aug 14;369(6505):812-817
pubmed: 32434946
Nature. 2021 Feb;590(7847):635-641
pubmed: 33429418
Immunity. 2021 Sep 14;54(9):2143-2158.e15
pubmed: 34453881
Nature. 2020 Sep;585(7824):268-272
pubmed: 32396922
JAMA Neurol. 2020 Jun 1;77(6):683-690
pubmed: 32275288
Nature. 2020 Sep;585(7824):273-276
pubmed: 32516797
Signal Transduct Target Ther. 2020 Oct 19;5(1):157
pubmed: 32814760