Delivery Mode Shapes the Composition of the Lower Airways Microbiota in Newborns.
caesarean section
delivery mode
lower airways
microbiota
vaginal delivery
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2021
2021
Historique:
received:
05
11
2021
accepted:
10
12
2021
entrez:
10
1
2022
pubmed:
11
1
2022
medline:
29
1
2022
Statut:
epublish
Résumé
Radical alterations in the human microbiota composition are well-known to be associated with many pathological conditions. If these aberrations are established at the time of birth, the risk of developing correlated pathologies throughout life is significantly increased. For this reason, all newborns should begin their lives with a proper microbiota in each body district. The present study aimed at demonstrating a correlation between the mode of delivery and the development of a well-balanced microbiota in the lower airways of newborns. 44 pregnant women were enrolled in this study. Microbiological comparative analysis was carried out on tracheobronchial secretions of babies born through vaginal delivery (VD) or caesarean section (CS). All samples showed the presence of bacterial DNA, regardless of the mode of delivery. No viable cultivable bacteria were isolated from the CS samples. On the contrary, VD allowed colonization of the lower airways by alive cultivable bacteria. The identification of bacterial species revealed that
Identifiants
pubmed: 35004360
doi: 10.3389/fcimb.2021.808390
pmc: PMC8733567
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
808390Informations de copyright
Copyright © 2021 Cardelli, Calvigioni, Vecchione, Macera, Mazzantini, Celandroni, Panattoni, Pistello, Maggi, Ghelardi and Mannella.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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