The short neuropeptide F regulates appetitive but not aversive responsiveness in a social insect.
Animal physiology
Behavioral neuroscience
Entomology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
21 Jan 2022
21 Jan 2022
Historique:
received:
09
09
2021
revised:
01
12
2021
accepted:
09
12
2021
entrez:
10
1
2022
pubmed:
11
1
2022
medline:
11
1
2022
Statut:
epublish
Résumé
The neuropeptide F (NPF) and its short version (sNPF) mediate food- and stress-related responses in solitary insects. In the honeybee, a social insect where food collection and defensive responses are socially regulated, only sNPF has an identified receptor. Here we increased artificially sNPF levels in honeybee foragers and studied the consequences of this manipulation in various forms of appetitive and aversive responsiveness. Increasing sNPF in partially fed bees turned them into the equivalent of starved animals, enhancing both their food consumption and responsiveness to appetitive gustatory and olfactory stimuli. Neural activity in the olfactory circuits of fed animals was reduced and could be rescued by sNPF treatment to the level of starved bees. In contrast, sNPF had no effect on responsiveness to nociceptive stimuli. Our results thus identify sNPF as a key modulator of hunger and food-related responses in bees, which are at the core of their foraging activities.
Identifiants
pubmed: 35005557
doi: 10.1016/j.isci.2021.103619
pii: S2589-0042(21)01589-3
pmc: PMC8719019
doi:
Banques de données
figshare
['10.6084/m9.figshare.16864408']
Types de publication
Journal Article
Langues
eng
Pagination
103619Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
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