Case report
EGFR
Neuroendocrine
Small cell lung cancer
Spontaneous transformation
Journal
JTO clinical and research reports
ISSN: 2666-3643
Titre abrégé: JTO Clin Res Rep
Pays: United States
ID NLM: 101769967
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
09
10
2021
revised:
22
11
2021
accepted:
29
11
2021
entrez:
10
1
2022
pubmed:
11
1
2022
medline:
11
1
2022
Statut:
epublish
Résumé
Lineage transformation from lung adenocarcinoma (LUAD) to SCLC is associated with resistance to EGFR tyrosine kinase inhibitors. In addition to loss of p53 and RB, transformed SCLCs are usually not dependent on EGFR signaling, which renders the tumors unresponsive to EGFR tyrosine kinase inhibitors. Here, we present a case of spontaneous transformation from
Identifiants
pubmed: 35005656
doi: 10.1016/j.jtocrr.2021.100264
pii: S2666-3643(21)00123-5
pmc: PMC8718492
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100264Informations de copyright
© 2021 The Authors.
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