Correlation of Somatostatin Receptor 1-5 Expression, [
immunohistochemistry
non-functional pancreatic neuroendocrine neoplasm
positron emission tomography
prospective study
somatostatin receptors
surgical management
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
29 Dec 2021
29 Dec 2021
Historique:
received:
03
12
2021
revised:
23
12
2021
accepted:
26
12
2021
entrez:
11
1
2022
pubmed:
12
1
2022
medline:
12
1
2022
Statut:
epublish
Résumé
The aim of this study was to correlate immunohistochemical (IHC) tissue levels of SSTR1-5 with the receptor density generated from [ Twenty-one patients with a total of thirty-five NF-PNEN-lesions and twenty-one histologically confirmed lymph node metastases (LN+) were included in this prospective study. Twenty patients were operated on, and one underwent endoscopic ultrasonography and core-needle biopsy. PET/CT with both [ Expression of SSTR1-5 was detected in 74%, 91%, 80%, 14%, and 77% of NF-PNENs. There was a concordance of SSTR2 IHC with positive/negative [ SSTR2 was the only SSTR subtype to correlate with [
Identifiants
pubmed: 35008325
pii: cancers14010162
doi: 10.3390/cancers14010162
pmc: PMC8750461
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Turku University Hospital Research Services
ID : 13920
Organisme : Mary and Georg C. Ehrnrooth Foundation
ID : 202110027
Organisme : The Finnish Medical Foundation
ID : 2547
Organisme : Cancer Foundation Finland
ID : WBS 4707973
Organisme : Liv&Hälsa Foundation
ID : WBS 4708047
Organisme : Helsinki University Hospital Research Fund
ID : TYH2021204
Organisme : Hus Diagnostic Centre Research Fund
ID : Y780021084
Références
Eur J Nucl Med Mol Imaging. 2009 Jan;36(1):48-52
pubmed: 18807033
Ital J Gastroenterol Hepatol. 1999 Oct;31 Suppl 2:S219-23
pubmed: 10604135
Horm Metab Res. 2010 Jul;42(8):599-606
pubmed: 20422506
Gut. 2002 Jan;50(1):52-60
pubmed: 11772967
Clin Cancer Res. 1999 Nov;5(11):3483-7
pubmed: 10589762
Eur J Endocrinol. 2005 Apr;152(4):645-54
pubmed: 15817922
Eur J Nucl Med Mol Imaging. 2011 Sep;38(9):1659-68
pubmed: 21626438
Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):59-72
pubmed: 27069766
Pancreas. 2015 May;44(4):648-54
pubmed: 25872131
Endocrinol Metab Clin North Am. 2018 Sep;47(3):463-470
pubmed: 30098710
J Nucl Med. 2016 Dec;57(12):1851-1857
pubmed: 27469355
Cancer. 2013 Dec 1;119(23):4094-102
pubmed: 24022344
Hum Pathol. 2015 Mar;46(3):390-6
pubmed: 25554089
Radiologe. 2010 Apr;50(4):349-54
pubmed: 20333502
Dig Liver Dis. 2010 Mar;42(3):220-5
pubmed: 19819769
Cancer Manag Res. 2018 Nov 13;10:5629-5638
pubmed: 30519109
Pancreas. 2017 Jan;46(1):42-47
pubmed: 27906872
JAMA Oncol. 2017 Oct 1;3(10):1335-1342
pubmed: 28448665
Pancreas. 2016 Feb;45(2):187-92
pubmed: 26474434
Mol Endocrinol. 2003 Jan;17(1):93-106
pubmed: 12511609
Oncol Rep. 2009 Feb;21(2):379-86
pubmed: 19148511
EJNMMI Res. 2019 Dec 23;9(1):116
pubmed: 31872324
Eur J Endocrinol. 2002 May;146(5):707-16
pubmed: 11980628
Neuroendocrinology. 2017 Feb 25;105(3):255-265
pubmed: 28237989
Medicine (Baltimore). 2015 Oct;94(40):e1281
pubmed: 26447992
Clin Cancer Res. 2010 Feb 1;16(3):978-85
pubmed: 20103666
Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):468-475
pubmed: 27539020
Am J Surg Pathol. 2012 Feb;36(2):242-52
pubmed: 22251942
Am J Surg Pathol. 2012 Sep;36(9):1359-63
pubmed: 22895268
Ann Surg. 2008 Mar;247(3):490-500
pubmed: 18376195
Appl Immunohistochem Mol Morphol. 2000 Jun;8(2):126-32
pubmed: 10937060
J Exp Clin Cancer Res. 2010 Mar 02;29:19
pubmed: 20196864
Pancreas. 2016 Nov;45(10):1386-1393
pubmed: 27622342
J Clin Endocrinol Metab. 2019 Jun 1;104(6):2083-2093
pubmed: 30657933
Theranostics. 2017 Mar 1;7(5):1149-1158
pubmed: 28435454
J Clin Endocrinol Metab. 2000 Oct;85(10):3882-91
pubmed: 11061553
J Histochem Cytochem. 2019 Oct;67(10):735-743
pubmed: 31381461
Ann Oncol. 2010 Mar;21(3):548-555
pubmed: 19759190