Specific Inhibition of VanZ-Mediated Resistance to Lipoglycopeptide Antibiotics.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
22 Dec 2021
Historique:
received: 22 11 2021
revised: 17 12 2021
accepted: 19 12 2021
entrez: 11 1 2022
pubmed: 12 1 2022
medline: 1 2 2022
Statut: epublish

Résumé

Teicoplanin is a natural lipoglycopeptide antibiotic with a similar activity spectrum as vancomycin; however, it has with the added benefit to the patient of low cytotoxicity. Both teicoplanin and vancomycin antibiotics are actively used in medical practice in the prophylaxis and treatment of severe life-threatening infections caused by gram-positive bacteria, including methicillin-resistant

Identifiants

pubmed: 35008521
pii: ijms23010097
doi: 10.3390/ijms23010097
pmc: PMC8744867
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Bacterial Proteins 0
Lipoglycopeptides 0
Teicoplanin 61036-62-2
Vancomycin 6Q205EH1VU

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Ministry of Health of the Czech Republic
ID : NU20-03-00309
Organisme : BIOCEV
ID : CZ.1.05/1.1.00/02.0109
Organisme : Institute of Biotechnology RVO
ID : 86652036
Organisme : Czech Science Foundation
ID : 20-09811Y
Organisme : Czech Academy of Sciences
ID : LQ200202002
Organisme : Czech Science Foundation
ID : 19-08176S

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Auteurs

Vishma Pratap Sur (VP)

Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.

Aninda Mazumdar (A)

Laboratory for Biology of Secondary Metabolism, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

Vladimir Vimberg (V)

Laboratory for Biology of Secondary Metabolism, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

Tommaso Stefani (T)

Laboratory for Biology of Secondary Metabolism, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

Ladislav Androvic (L)

Department of Polymer and Colloid Immunotherapeutics, Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovskeho namesti 2, 162 06 Prague, Czech Republic.

Lucie Kracikova (L)

Department of Polymer and Colloid Immunotherapeutics, Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovskeho namesti 2, 162 06 Prague, Czech Republic.
Department of Polymers, Faculty of Chemical Technology, University of Chemistry and Technology, Technicka 5, 166 28 Prague, Czech Republic.

Richard Laga (R)

Department of Polymer and Colloid Immunotherapeutics, Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovskeho namesti 2, 162 06 Prague, Czech Republic.

Zdenek Kamenik (Z)

Laboratory for Biology of Secondary Metabolism, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

Katerina Komrskova (K)

Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Prumyslova 595, 252 50 Vestec, Czech Republic.
Department of Zoology, Faculty of Science, Charles University, Vinicna 7, 128 44 Prague, Czech Republic.

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Classifications MeSH