Acute Myeloid Leukemia-Related Proteins Modified by Ubiquitin and Ubiquitin-like Proteins.
ISGylation
NEDDylation
SUMOylation
deubiquitination
ubiquitination
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
03 Jan 2022
03 Jan 2022
Historique:
received:
27
10
2021
revised:
24
12
2021
accepted:
30
12
2021
entrez:
11
1
2022
pubmed:
12
1
2022
medline:
15
2
2022
Statut:
epublish
Résumé
Acute myeloid leukemia (AML), the most common form of an acute leukemia, is a malignant disorder of stem cell precursors of the myeloid lineage. Ubiquitination is one of the post-translational modifications (PTMs), and the ubiquitin-like proteins (Ubls; SUMO, NEDD8, and ISG15) play a critical role in various cellular processes, including autophagy, cell-cycle control, DNA repair, signal transduction, and transcription. Also, the importance of Ubls in AML is increasing, with the growing research defining the effect of Ubls in AML. Numerous studies have actively reported that AML-related mutated proteins are linked to Ub and Ubls. The current review discusses the roles of proteins associated with protein ubiquitination, modifications by Ubls in AML, and substrates that can be applied for therapeutic targets in AML.
Identifiants
pubmed: 35008940
pii: ijms23010514
doi: 10.3390/ijms23010514
pmc: PMC8745615
pii:
doi:
Substances chimiques
Ubiquitin
0
Ubiquitins
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministry of Education
ID : NRF-2019R1A6A1A03032888
Références
Oncogene. 2018 May;37(19):2532-2544
pubmed: 29459712
Methods Mol Biol. 2012;832:141-9
pubmed: 22350882
Leukemia. 2019 Feb;33(2):299-312
pubmed: 30651634
Life Sci. 2020 Sep 15;257:118021
pubmed: 32621919
Nat Immunol. 2014 Jun;15(6):562-70
pubmed: 24777531
Mol Cell. 2007 Sep 21;27(6):1014-23
pubmed: 17889673
Life Sci. 2020 Sep 15;257:118041
pubmed: 32622945
BMB Rep. 2008 Jun 30;41(6):435-43
pubmed: 18593526
Oncol Rep. 2015 May;33(5):2099-106
pubmed: 25760953
Development. 2020 Jan 15;147(2):
pubmed: 31941705
Haematologica. 2010 Mar;95(3):415-23
pubmed: 20007139
J Cell Mol Med. 2020 Dec;24(23):13813-13823
pubmed: 33135363
Prog Tumor Res. 2016;43:87-100
pubmed: 27595359
FASEB J. 2010 Apr;24(4):981-93
pubmed: 19940261
Cell. 2010 Feb 5;140(3):384-96
pubmed: 20096447
Science. 2019 May 17;364(6441):
pubmed: 31097636
Cancers (Basel). 2019 Nov 03;11(11):
pubmed: 31684170
J Gastroenterol Hepatol. 2010 Nov;25(11):1800-5
pubmed: 21039844
Front Oncol. 2013 Jan 04;2:210
pubmed: 23316480
J Cell Sci. 2018 Mar 20;131(6):
pubmed: 29559551
Nature. 2011 Mar 31;471(7340):591-6
pubmed: 21455173
Cell Death Differ. 2020 Jun;27(6):1747-1764
pubmed: 31748695
Front Mol Biosci. 2021 Mar 26;8:652284
pubmed: 33842551
J Cell Sci. 2003 Apr 1;116(Pt 7):1175-86
pubmed: 12615961
Front Oncol. 2020 Feb 27;10:149
pubmed: 32175272
Cell Death Dis. 2015 Feb 19;6:e1654
pubmed: 25695607
Transl Oncol. 2019 Apr;12(4):602-613
pubmed: 30699367
Biochem Biophys Res Commun. 2017 Oct 14;492(2):178-183
pubmed: 28807825
Front Cell Dev Biol. 2020 Jun 26;8:529
pubmed: 32671073
Leukemia. 2017 Feb;31(2):491-495
pubmed: 27733775
J Mol Biol. 2020 Jan 3;432(1):80-103
pubmed: 31310766
Exp Cell Res. 2018 Oct 15;371(2):409-416
pubmed: 30179602
Cell Res. 2014 Apr;24(4):400-16
pubmed: 24366338
J Clin Invest. 2018 Aug 1;128(8):3250-3264
pubmed: 29878897
Genes Genomics. 2019 Aug;41(8):879-884
pubmed: 31028655
Blood Adv. 2018 Oct 23;2(20):2724-2731
pubmed: 30337300
Cancer Res. 2010 Dec 1;70(23):9875-85
pubmed: 20935222
Int J Mol Sci. 2017 Feb 17;18(2):
pubmed: 28218667
Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15665-70
pubmed: 9861027
Mol Cell. 2016 Feb 18;61(4):614-624
pubmed: 26876938
Front Pharmacol. 2020 Sep 15;11:561306
pubmed: 33041800
Biochim Biophys Acta. 2014 Jan;1843(1):47-60
pubmed: 23747565
BMC Cancer. 2015 Nov 11;15:893
pubmed: 26559765
FEBS J. 2009 Nov;276(21):6074-83
pubmed: 19788416
Leukemia. 2013 Apr;27(5):1037-43
pubmed: 23183427
Oncogene. 2021 Feb;40(7):1217-1230
pubmed: 33420360
Leukemia. 2018 Apr;32(4):911-919
pubmed: 29209041
Cancer. 2008 Oct 1;113(7 Suppl):1933-52
pubmed: 18798533
Bioorg Med Chem Lett. 2014 Feb 15;24(4):1094-7
pubmed: 24468414
Int J Mol Sci. 2020 May 30;21(11):
pubmed: 32486158
Cell Rep. 2013 Oct 17;5(1):224-36
pubmed: 24075993
Front Oncol. 2012 Jan 31;2:5
pubmed: 22649774
Int J Mol Sci. 2021 Jun 08;22(12):
pubmed: 34201062
N Engl J Med. 2020 Dec 31;383(27):2628-2638
pubmed: 33108101
Oncol Lett. 2019 Nov;18(5):4659-4666
pubmed: 31611975
CA Cancer J Clin. 2020 Jan;70(1):7-30
pubmed: 31912902
Front Cell Neurosci. 2017 Jan 10;10:301
pubmed: 28119569
Anim Cells Syst (Seoul). 2019 Sep 6;23(5):311-317
pubmed: 31700696
Science. 2003 Jun 6;300(5625):1574-7
pubmed: 12791994
Cell Commun Signal. 2019 Jul 29;17(1):86
pubmed: 31358016
Nature. 2010 Jan 7;463(7277):54-60
pubmed: 20054389
Oncogene. 2008 Apr 10;27(17):2401-11
pubmed: 17968316
PLoS Biol. 2004 Jan;2(1):E2
pubmed: 14737182
J Biol Chem. 2012 Mar 9;287(11):8001-12
pubmed: 22267730
JCI Insight. 2021 Mar 8;6(5):
pubmed: 33476303
J Blood Med. 2021 May 05;12:245-255
pubmed: 33981169
N Engl J Med. 2012 Mar 22;366(12):1079-89
pubmed: 22417203
Science. 2019 Apr 12;364(6436):188-193
pubmed: 30975888
J Biol Chem. 2002 Mar 22;277(12):9976-81
pubmed: 11788588
J Clin Oncol. 2013 Jun 10;31(17):2086-93
pubmed: 23650424
Leukemia. 2019 Jan;33(1):37-51
pubmed: 29884901
Biochem Biophys Res Commun. 2019 Jun 11;513(4):1063-1069
pubmed: 31010676
Cell Res. 2016 Apr;26(4):399-422
pubmed: 27012465
Oncogene. 2018 May;37(19):2559-2572
pubmed: 29467492
Cancer Res. 2014 Jan 1;74(1):272-86
pubmed: 24197134
Clin Cancer Res. 2015 Jan 15;21(2):439-47
pubmed: 25388161
Blood Adv. 2018 Nov 13;2(21):2890-2903
pubmed: 30385433
Annu Rev Biochem. 2009;78:363-97
pubmed: 19489724
Cell Rep. 2020 Feb 25;30(8):2776-2790.e6
pubmed: 32101751
Growth Horm IGF Res. 2019 Apr;45:6-16
pubmed: 30735831
Mol Cell. 2005 Apr 1;18(1):1-12
pubmed: 15808504
Physiol Rev. 2007 Jan;87(1):245-313
pubmed: 17237347
Cancer Res. 2005 Jul 1;65(13):5835-40
pubmed: 15994960
Oncol Lett. 2020 Mar;19(3):1657-1664
pubmed: 32194657
J Clin Invest. 2014 Aug;124(8):3407-18
pubmed: 24960159
Structure. 2016 Mar 1;24(3):423-36
pubmed: 26876099
Br J Cancer. 2014 Oct 14;111(8):1663-72
pubmed: 25225902
Mol Cancer. 2019 Apr 3;18(1):77
pubmed: 30943988
Cell Discov. 2020 May 5;6:23
pubmed: 32377373
Blood. 2018 Jul 26;132(4):423-434
pubmed: 29844011
Nat Chem Biol. 2017 Dec;13(12):1207-1215
pubmed: 28967922
J Cell Sci. 2017 Sep 15;130(18):2961-2969
pubmed: 28842471
EMBO Rep. 2007 Jun;8(6):550-5
pubmed: 17545995
Blood. 2010 Aug 26;116(8):1321-8
pubmed: 20410507
Blood. 2003 Nov 1;102(9):3323-32
pubmed: 12816872
Biochem J. 2014 Mar 15;458(3):421-37
pubmed: 24576094
Med Oncol. 2021 May 17;38(6):69
pubmed: 34002296
Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):348-355
pubmed: 27913501
Blood. 2018 Jun 14;131(24):2698-2711
pubmed: 29720484
Sci Adv. 2020 Sep 18;6(38):
pubmed: 32948596
Trends Cell Biol. 2011 Nov;21(11):656-63
pubmed: 21978762
Leukemia. 2015 Oct;29(10):1981-92
pubmed: 25971362
Blood. 2007 Aug 1;110(3):1004-12
pubmed: 17446348
Science. 2006 Jun 23;312(5781):1763-6
pubmed: 16794074
J Biol Chem. 2009 Mar 27;284(13):8223-7
pubmed: 19008217
J Cancer Res Clin Oncol. 2011 Aug;137(8):1245-53
pubmed: 21691749
Circ Res. 2010 May 14;106(9):1516-23
pubmed: 20360254
N Engl J Med. 2016 Jun 9;374(23):2209-2221
pubmed: 27276561
Clin Cancer Res. 2015 Apr 15;21(8):1789-94
pubmed: 25477533
Cancer Res. 2003 Mar 15;63(6):1339-44
pubmed: 12649196
Exp Hematol. 2015 Mar;43(3):191-206.e1
pubmed: 25534201
Oncotarget. 2017 Sep 26;8(54):92018-92031
pubmed: 29190894
Blood. 2016 Jan 7;127(1):1
pubmed: 26660430
Leukemia. 2014 Aug;28(8):1586-95
pubmed: 24487413
Cancer Lett. 2015 Feb 1;357(1):297-306
pubmed: 25448401
J Hematol Oncol. 2016 Nov 17;9(1):125
pubmed: 27855695
FEBS J. 2016 Oct;283(19):3567-3586
pubmed: 27459543
Blood. 2010 Nov 4;116(18):3622-6
pubmed: 20656931
Annu Rev Biochem. 2017 Jun 20;86:129-157
pubmed: 28375744
EMBO J. 2019 Feb 15;38(4):
pubmed: 30692133
Curr Opin Cell Biol. 2009 Dec;21(6):816-24
pubmed: 19775879
Mol Cancer Ther. 2008 Apr;7(4):905-14
pubmed: 18413804
Cancer Lett. 2019 Jul 1;453:84-94
pubmed: 30946869
J Clin Med. 2015 Mar 12;4(3):460-78
pubmed: 26239249
Cell Death Differ. 2016 Aug;23(8):1257-64
pubmed: 27285106
Methods Enzymol. 2005;398:491-9
pubmed: 16275353
Leukemia. 2021 Jul;35(7):1829-1842
pubmed: 33811246
PLoS Pathog. 2020 Oct 26;16(10):e1008970
pubmed: 33104725
Blood. 2002 Sep 1;100(5):1532-42
pubmed: 12176867
Br J Haematol. 2013 Feb;160(3):303-20
pubmed: 23240632
Cell. 2013 Aug 1;154(3):556-68
pubmed: 23911321
Proc Natl Acad Sci U S A. 2019 May 21;116(21):10494-10503
pubmed: 31064876
J Clin Oncol. 2012 Apr 20;30(12):1350-7
pubmed: 22430270
Blood Rev. 2013 Jan;27(1):13-22
pubmed: 23261068
FEBS Lett. 2010 Apr 16;584(8):1565-70
pubmed: 20226183
Oncotarget. 2016 Jul 12;7(28):44848-44856
pubmed: 27057639
Mol Cell. 2017 Oct 5;68(1):233-246.e5
pubmed: 28943312
Cancer Res. 2004 Oct 15;64(20):7226-30
pubmed: 15492238
J Biol Chem. 2000 Mar 17;275(11):7462-5
pubmed: 10713047
Mol Cancer Res. 2021 Feb;19(2):261-273
pubmed: 33188146
Mol Cell Biol. 2020 Oct 13;40(21):
pubmed: 32839293
Mol Cancer Ther. 2019 Jul;18(7):1205-1216
pubmed: 31092565
Blood. 2010 May 6;115(18):3796-800
pubmed: 20203261
Int J Mol Sci. 2020 Nov 11;21(22):
pubmed: 33187090
J Clin Oncol. 2005 Dec 20;23(36):9234-42
pubmed: 16275934
Cell Mol Life Sci. 2018 Sep;75(17):3121-3141
pubmed: 29858610
Mol Oncol. 2020 Jan;14(1):197-210
pubmed: 31721429
Leuk Res. 2010 Jun;34(6):752-6
pubmed: 19878996
Am J Transl Res. 2019 Mar 15;11(3):1668-1682
pubmed: 30972192
Nat Cell Biol. 2007 Jul;9(7):765-74
pubmed: 17558397
Oncol Rep. 2014 Dec;32(6):2726-34
pubmed: 25241857
Blood. 2013 Sep 5;122(10):1750-60
pubmed: 23884858
Am J Cancer Res. 2019 Jan 01;9(1):94-107
pubmed: 30755814
J Biol Chem. 1987 Aug 15;262(23):11315-23
pubmed: 2440890
Free Radic Biol Med. 2006 Jan 15;40(2):183-92
pubmed: 16413400
Exp Cell Res. 2011 Apr 15;317(7):1060-70
pubmed: 21192925
Nat Med. 2014 Nov;20(11):1242-53
pubmed: 25375928
Nat Chem Biol. 2021 Aug;17(8):896-905
pubmed: 34239127
Int J Oncol. 2018 Apr;52(4):1081-1094
pubmed: 29484374
Blood. 2005 Aug 1;106(3):899-902
pubmed: 15831697
Chem Rev. 2018 Feb 14;118(3):889-918
pubmed: 28234446
Oncol Lett. 2018 Jan;15(1):41-47
pubmed: 29285186
Science. 2015 Apr 10;348(6231):1250834
pubmed: 25859050
Blood. 2011 Oct 6;118(14):3803-10
pubmed: 21828143
Front Pediatr. 2017 Feb 09;5:4
pubmed: 28232907
NPJ Genom Med. 2020 Dec 9;5(1):53
pubmed: 33298948
Blood. 2005 Aug 15;106(4):1154-63
pubmed: 15870183
Oncotarget. 2015 Oct 13;6(31):31428-40
pubmed: 25537507
Transcription. 2015;6(5):102-5
pubmed: 26507581
Trends Biochem Sci. 2007 Jun;32(6):286-95
pubmed: 17499995
Sci Rep. 2020 Nov 26;10(1):20670
pubmed: 33244139
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14395-14404
pubmed: 32513696
Curr Cancer Drug Targets. 2016;16(2):157-74
pubmed: 26560116
J Cell Biochem. 2020 Apr;121(4):2839-2850
pubmed: 31692040
Leukemia. 2017 Feb;31(2):502-505
pubmed: 27773928
Biochim Biophys Acta. 2004 Nov 29;1695(1-3):113-31
pubmed: 15571812
Open Biol. 2017 Oct;7(10):
pubmed: 29021212
Int J Med Sci. 2020 Jan 20;17(3):347-353
pubmed: 32132870
J Biol Chem. 2021 Sep;297(3):101077
pubmed: 34391779
J Virol. 2018 Jul 17;92(15):
pubmed: 29743376
J Biol Chem. 2012 May 25;287(22):18230-48
pubmed: 22493287
Sci Rep. 2015 Aug 04;5:12793
pubmed: 26238070
EMBO Mol Med. 2016 Aug 01;8(8):851-62
pubmed: 27317434
Theranostics. 2020 Jan 1;10(3):1046-1059
pubmed: 31938050
Leukemia. 2021 Feb;35(2):417-432
pubmed: 32447346
Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14807-12
pubmed: 10611294
Oncogene. 2018 May;37(18):2422-2431
pubmed: 29449692
Cancer Res. 2020 Jun 1;80(11):2204-2216
pubmed: 32217697
Nat Commun. 2021 Sep 13;12(1):5397
pubmed: 34518534
Exp Hematol Oncol. 2020 Mar 27;9:4
pubmed: 32231866
Blood. 2013 Mar 28;121(13):2452-61
pubmed: 23349393
Int J Hematol. 2011 Aug;94(2):134-141
pubmed: 21823042
Cell Cycle. 2012 Mar 15;11(6):1142-50
pubmed: 22370482
Biochemistry. 2014 May 20;53(19):3199-217
pubmed: 24787148
Nat Struct Mol Biol. 2012 Jan 22;19(2):184-92
pubmed: 22266821